Abstract
Cryogenic detectors have recently been applied for the first time as ion detectors in time-of-flight mass spectrometry (TOF-MS). Because of their energy sensitivity cryogenic detectors are expected to have near 100% efficiency even for very large, slow-moving molecules, in contrast to microchannel plates whose efficiency drops considerably at large mass. Thus, cryogenic detectors could contribute to extending the mass range accessible by TOF-MS and help improving detection limits. In addition, the energy resolution provided by cryogenic detectors can be used for charge discrimination and studies of ion fragmentation, ion-detector interaction, and internal energies of large molecular ions. Cryogenic detectors could therefore prove to be a valuable diagnostic tool in TOF-MS. Here I summarize the results of recent demonstration experiments.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 375-384 |
| Number of pages | 10 |
| Journal | Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment |
| Volume | 444 |
| Issue number | 1 |
| DOIs | |
| State | Published - Apr 7 2000 |
| Externally published | Yes |
| Event | 8th International Workshop on Low Temperature Detectors (LTD-8) - Dalfsen, Neth Duration: Aug 15 1999 → Aug 20 1999 |
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ASJC Scopus subject areas
- Nuclear and High Energy Physics
- Instrumentation
Cite this
Mass spectrometry with cryogenic detectors. / Frank, Matthias.
In: Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 444, No. 1, 07.04.2000, p. 375-384.Research output: Contribution to journal › Conference article
}
TY - JOUR
T1 - Mass spectrometry with cryogenic detectors
AU - Frank, Matthias
PY - 2000/4/7
Y1 - 2000/4/7
N2 - Cryogenic detectors have recently been applied for the first time as ion detectors in time-of-flight mass spectrometry (TOF-MS). Because of their energy sensitivity cryogenic detectors are expected to have near 100% efficiency even for very large, slow-moving molecules, in contrast to microchannel plates whose efficiency drops considerably at large mass. Thus, cryogenic detectors could contribute to extending the mass range accessible by TOF-MS and help improving detection limits. In addition, the energy resolution provided by cryogenic detectors can be used for charge discrimination and studies of ion fragmentation, ion-detector interaction, and internal energies of large molecular ions. Cryogenic detectors could therefore prove to be a valuable diagnostic tool in TOF-MS. Here I summarize the results of recent demonstration experiments.
AB - Cryogenic detectors have recently been applied for the first time as ion detectors in time-of-flight mass spectrometry (TOF-MS). Because of their energy sensitivity cryogenic detectors are expected to have near 100% efficiency even for very large, slow-moving molecules, in contrast to microchannel plates whose efficiency drops considerably at large mass. Thus, cryogenic detectors could contribute to extending the mass range accessible by TOF-MS and help improving detection limits. In addition, the energy resolution provided by cryogenic detectors can be used for charge discrimination and studies of ion fragmentation, ion-detector interaction, and internal energies of large molecular ions. Cryogenic detectors could therefore prove to be a valuable diagnostic tool in TOF-MS. Here I summarize the results of recent demonstration experiments.
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UR - http://www.scopus.com/inward/citedby.url?scp=0033748963&partnerID=8YFLogxK
U2 - 10.1016/S0168-9002(99)01409-6
DO - 10.1016/S0168-9002(99)01409-6
M3 - Conference article
VL - 444
SP - 375
EP - 384
JO - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
JF - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
SN - 0168-9002
IS - 1
ER -