Mass spectrometry with cryogenic detectors

Research output: Contribution to journalConference article

17 Citations (Scopus)

Abstract

Cryogenic detectors have recently been applied for the first time as ion detectors in time-of-flight mass spectrometry (TOF-MS). Because of their energy sensitivity cryogenic detectors are expected to have near 100% efficiency even for very large, slow-moving molecules, in contrast to microchannel plates whose efficiency drops considerably at large mass. Thus, cryogenic detectors could contribute to extending the mass range accessible by TOF-MS and help improving detection limits. In addition, the energy resolution provided by cryogenic detectors can be used for charge discrimination and studies of ion fragmentation, ion-detector interaction, and internal energies of large molecular ions. Cryogenic detectors could therefore prove to be a valuable diagnostic tool in TOF-MS. Here I summarize the results of recent demonstration experiments.

Original languageEnglish (US)
Pages (from-to)375-384
Number of pages10
JournalNuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Volume444
Issue number1
DOIs
StatePublished - Apr 7 2000
Externally publishedYes
Event8th International Workshop on Low Temperature Detectors (LTD-8) - Dalfsen, Neth
Duration: Aug 15 1999Aug 20 1999

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Cryogenics
cryogenics
Mass spectrometry
mass spectroscopy
Detectors
detectors
Ions
ions
microchannel plates
Microchannels
internal energy
molecular ions
discrimination
fragmentation
Demonstrations
Molecules
energy
molecules
Experiments
interactions

ASJC Scopus subject areas

  • Nuclear and High Energy Physics
  • Instrumentation

Cite this

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abstract = "Cryogenic detectors have recently been applied for the first time as ion detectors in time-of-flight mass spectrometry (TOF-MS). Because of their energy sensitivity cryogenic detectors are expected to have near 100{\%} efficiency even for very large, slow-moving molecules, in contrast to microchannel plates whose efficiency drops considerably at large mass. Thus, cryogenic detectors could contribute to extending the mass range accessible by TOF-MS and help improving detection limits. In addition, the energy resolution provided by cryogenic detectors can be used for charge discrimination and studies of ion fragmentation, ion-detector interaction, and internal energies of large molecular ions. Cryogenic detectors could therefore prove to be a valuable diagnostic tool in TOF-MS. Here I summarize the results of recent demonstration experiments.",
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AU - Frank, Matthias

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N2 - Cryogenic detectors have recently been applied for the first time as ion detectors in time-of-flight mass spectrometry (TOF-MS). Because of their energy sensitivity cryogenic detectors are expected to have near 100% efficiency even for very large, slow-moving molecules, in contrast to microchannel plates whose efficiency drops considerably at large mass. Thus, cryogenic detectors could contribute to extending the mass range accessible by TOF-MS and help improving detection limits. In addition, the energy resolution provided by cryogenic detectors can be used for charge discrimination and studies of ion fragmentation, ion-detector interaction, and internal energies of large molecular ions. Cryogenic detectors could therefore prove to be a valuable diagnostic tool in TOF-MS. Here I summarize the results of recent demonstration experiments.

AB - Cryogenic detectors have recently been applied for the first time as ion detectors in time-of-flight mass spectrometry (TOF-MS). Because of their energy sensitivity cryogenic detectors are expected to have near 100% efficiency even for very large, slow-moving molecules, in contrast to microchannel plates whose efficiency drops considerably at large mass. Thus, cryogenic detectors could contribute to extending the mass range accessible by TOF-MS and help improving detection limits. In addition, the energy resolution provided by cryogenic detectors can be used for charge discrimination and studies of ion fragmentation, ion-detector interaction, and internal energies of large molecular ions. Cryogenic detectors could therefore prove to be a valuable diagnostic tool in TOF-MS. Here I summarize the results of recent demonstration experiments.

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JO - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

JF - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

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