Markedly increased central corneal thickness: An unrecognized finding in congenital aniridia

James D Brandt, Lourdes A. Casuso, Donald L. Budenz

Research output: Contribution to journalArticle

63 Citations (Scopus)

Abstract

PURPOSE: To describe central corneal thickness among patients diagnosed with congenital aniridia. DESIGN: Prospective noninterventional case series. METHODS: We identified patients carrying the clinical diagnosis of congenital aniridia and performed complete ophthalmic examinations. Eyes with known corneal pathology were excluded. Central corneal thickness was determined as the mean of five measurements per eye, acquired by matching ultrasonic pachymeters at two clinical sites. RESULTS: Seventeen patients were identified at two sites; 32 eyes qualified for inclusion. The average central corneal thickness of the qualifying eyes was 631.6 ± 50.8 μM. CONCLUSION: Markedly increased central corneal thickness appears to be a previously unrecognized aspect of congenital aniridia. This may lead to incorrect estimates of intraocular pressure by applanation techniques and highlights the importance of monitoring patients with aniridia for the development of glaucoma through regular gonioscopy and optic nerve examination.

Original languageEnglish (US)
Pages (from-to)348-350
Number of pages3
JournalAmerican Journal of Ophthalmology
Volume137
Issue number2
DOIs
StatePublished - Feb 2004

Fingerprint

Aniridia
Gonioscopy
Physiologic Monitoring
Optic Nerve
Intraocular Pressure
Ultrasonics
Glaucoma
Pathology

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Markedly increased central corneal thickness : An unrecognized finding in congenital aniridia. / Brandt, James D; Casuso, Lourdes A.; Budenz, Donald L.

In: American Journal of Ophthalmology, Vol. 137, No. 2, 02.2004, p. 348-350.

Research output: Contribution to journalArticle

@article{7c67aae5805b48f590f6c0e6a767889a,
title = "Markedly increased central corneal thickness: An unrecognized finding in congenital aniridia",
abstract = "PURPOSE: To describe central corneal thickness among patients diagnosed with congenital aniridia. DESIGN: Prospective noninterventional case series. METHODS: We identified patients carrying the clinical diagnosis of congenital aniridia and performed complete ophthalmic examinations. Eyes with known corneal pathology were excluded. Central corneal thickness was determined as the mean of five measurements per eye, acquired by matching ultrasonic pachymeters at two clinical sites. RESULTS: Seventeen patients were identified at two sites; 32 eyes qualified for inclusion. The average central corneal thickness of the qualifying eyes was 631.6 ± 50.8 μM. CONCLUSION: Markedly increased central corneal thickness appears to be a previously unrecognized aspect of congenital aniridia. This may lead to incorrect estimates of intraocular pressure by applanation techniques and highlights the importance of monitoring patients with aniridia for the development of glaucoma through regular gonioscopy and optic nerve examination.",
author = "Brandt, {James D} and Casuso, {Lourdes A.} and Budenz, {Donald L.}",
year = "2004",
month = "2",
doi = "10.1016/j.ajo.2003.09.038",
language = "English (US)",
volume = "137",
pages = "348--350",
journal = "American Journal of Ophthalmology",
issn = "0002-9394",
publisher = "Elsevier USA",
number = "2",

}

TY - JOUR

T1 - Markedly increased central corneal thickness

T2 - An unrecognized finding in congenital aniridia

AU - Brandt, James D

AU - Casuso, Lourdes A.

AU - Budenz, Donald L.

PY - 2004/2

Y1 - 2004/2

N2 - PURPOSE: To describe central corneal thickness among patients diagnosed with congenital aniridia. DESIGN: Prospective noninterventional case series. METHODS: We identified patients carrying the clinical diagnosis of congenital aniridia and performed complete ophthalmic examinations. Eyes with known corneal pathology were excluded. Central corneal thickness was determined as the mean of five measurements per eye, acquired by matching ultrasonic pachymeters at two clinical sites. RESULTS: Seventeen patients were identified at two sites; 32 eyes qualified for inclusion. The average central corneal thickness of the qualifying eyes was 631.6 ± 50.8 μM. CONCLUSION: Markedly increased central corneal thickness appears to be a previously unrecognized aspect of congenital aniridia. This may lead to incorrect estimates of intraocular pressure by applanation techniques and highlights the importance of monitoring patients with aniridia for the development of glaucoma through regular gonioscopy and optic nerve examination.

AB - PURPOSE: To describe central corneal thickness among patients diagnosed with congenital aniridia. DESIGN: Prospective noninterventional case series. METHODS: We identified patients carrying the clinical diagnosis of congenital aniridia and performed complete ophthalmic examinations. Eyes with known corneal pathology were excluded. Central corneal thickness was determined as the mean of five measurements per eye, acquired by matching ultrasonic pachymeters at two clinical sites. RESULTS: Seventeen patients were identified at two sites; 32 eyes qualified for inclusion. The average central corneal thickness of the qualifying eyes was 631.6 ± 50.8 μM. CONCLUSION: Markedly increased central corneal thickness appears to be a previously unrecognized aspect of congenital aniridia. This may lead to incorrect estimates of intraocular pressure by applanation techniques and highlights the importance of monitoring patients with aniridia for the development of glaucoma through regular gonioscopy and optic nerve examination.

UR - http://www.scopus.com/inward/record.url?scp=1242316165&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=1242316165&partnerID=8YFLogxK

U2 - 10.1016/j.ajo.2003.09.038

DO - 10.1016/j.ajo.2003.09.038

M3 - Article

C2 - 14962429

AN - SCOPUS:1242316165

VL - 137

SP - 348

EP - 350

JO - American Journal of Ophthalmology

JF - American Journal of Ophthalmology

SN - 0002-9394

IS - 2

ER -