Abstract
Prostaglandins and prostacyclin are metabolites of arachidonic acid and exert a variety of actions to maintain local homeostasis in the body. Their actions are mediated by cell surface receptors specific to the respective ligands. Using a panel of interspecific backcross mice, we have mapped the prostaglandin D receptor gene (Ptgdr), prostaglandin E receptor subtype EP1 gene (Ptgerep1), prostaglandin F receptor gene (Ptgfr), and prostacyclin receptor gene (Ptgir). Ptgdr mapped to proximal Chr 14, Ptgfr mapped to distal Chr 3, Ptgerep1 mapped to middle Chr 8, and Ptgir mapped to proximal Chr 7.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 285-288 |
| Number of pages | 4 |
| Journal | Genomics |
| Volume | 32 |
| Issue number | 2 |
| DOIs | |
| State | Published - Mar 1 1996 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Genetics
Cite this
Mapping of the genes encoding mouse prostaglandin D, E, and F and prostacyclin receptors. / Ishikawa, Tomo O.; Tamai, Yoshitaka; Rochelle, Julie M.; Hirata, Masakazu; Namba, Tsunehisa; Sugimoto, Yukihiko; Ichikawa, Atsushi; Narumiya, Shuh; Taketo, Makoto M.; Seldin, Michael F.
In: Genomics, Vol. 32, No. 2, 01.03.1996, p. 285-288.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Mapping of the genes encoding mouse prostaglandin D, E, and F and prostacyclin receptors
AU - Ishikawa, Tomo O.
AU - Tamai, Yoshitaka
AU - Rochelle, Julie M.
AU - Hirata, Masakazu
AU - Namba, Tsunehisa
AU - Sugimoto, Yukihiko
AU - Ichikawa, Atsushi
AU - Narumiya, Shuh
AU - Taketo, Makoto M.
AU - Seldin, Michael F
PY - 1996/3/1
Y1 - 1996/3/1
N2 - Prostaglandins and prostacyclin are metabolites of arachidonic acid and exert a variety of actions to maintain local homeostasis in the body. Their actions are mediated by cell surface receptors specific to the respective ligands. Using a panel of interspecific backcross mice, we have mapped the prostaglandin D receptor gene (Ptgdr), prostaglandin E receptor subtype EP1 gene (Ptgerep1), prostaglandin F receptor gene (Ptgfr), and prostacyclin receptor gene (Ptgir). Ptgdr mapped to proximal Chr 14, Ptgfr mapped to distal Chr 3, Ptgerep1 mapped to middle Chr 8, and Ptgir mapped to proximal Chr 7.
AB - Prostaglandins and prostacyclin are metabolites of arachidonic acid and exert a variety of actions to maintain local homeostasis in the body. Their actions are mediated by cell surface receptors specific to the respective ligands. Using a panel of interspecific backcross mice, we have mapped the prostaglandin D receptor gene (Ptgdr), prostaglandin E receptor subtype EP1 gene (Ptgerep1), prostaglandin F receptor gene (Ptgfr), and prostacyclin receptor gene (Ptgir). Ptgdr mapped to proximal Chr 14, Ptgfr mapped to distal Chr 3, Ptgerep1 mapped to middle Chr 8, and Ptgir mapped to proximal Chr 7.
UR - http://www.scopus.com/inward/record.url?scp=17644441130&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=17644441130&partnerID=8YFLogxK
U2 - 10.1006/geno.1996.0118
DO - 10.1006/geno.1996.0118
M3 - Article
C2 - 8833158
AN - SCOPUS:17644441130
VL - 32
SP - 285
EP - 288
JO - Genomics
JF - Genomics
SN - 0888-7543
IS - 2
ER -