Mapping of the genes encoding mouse prostaglandin D, E, and F and prostacyclin receptors

Tomo O. Ishikawa, Yoshitaka Tamai, Julie M. Rochelle, Masakazu Hirata, Tsunehisa Namba, Yukihiko Sugimoto, Atsushi Ichikawa, Shuh Narumiya, Makoto M. Taketo, Michael F Seldin

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Prostaglandins and prostacyclin are metabolites of arachidonic acid and exert a variety of actions to maintain local homeostasis in the body. Their actions are mediated by cell surface receptors specific to the respective ligands. Using a panel of interspecific backcross mice, we have mapped the prostaglandin D receptor gene (Ptgdr), prostaglandin E receptor subtype EP1 gene (Ptgerep1), prostaglandin F receptor gene (Ptgfr), and prostacyclin receptor gene (Ptgir). Ptgdr mapped to proximal Chr 14, Ptgfr mapped to distal Chr 3, Ptgerep1 mapped to middle Chr 8, and Ptgir mapped to proximal Chr 7.

Original languageEnglish (US)
Pages (from-to)285-288
Number of pages4
JournalGenomics
Volume32
Issue number2
DOIs
StatePublished - Mar 1 1996
Externally publishedYes

ASJC Scopus subject areas

  • Genetics

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    Ishikawa, T. O., Tamai, Y., Rochelle, J. M., Hirata, M., Namba, T., Sugimoto, Y., Ichikawa, A., Narumiya, S., Taketo, M. M., & Seldin, M. F. (1996). Mapping of the genes encoding mouse prostaglandin D, E, and F and prostacyclin receptors. Genomics, 32(2), 285-288. https://doi.org/10.1006/geno.1996.0118