Mapping of the genes encoding mouse prostaglandin D, E, and F and prostacyclin receptors

Tomo O. Ishikawa; Yoshitaka Tamai; Julie M. Rochelle; Masakazu Hirata; Tsunehisa Namba; Yukihiko Sugimoto; Atsushi Ichikawa; Shuh Narumiya; Makoto M. Taketo; Michael F Seldin

doi:10.1006/geno.1996.0118

Mapping of the genes encoding mouse prostaglandin D, E, and F and prostacyclin receptors

Tomo O. Ishikawa, Yoshitaka Tamai, Julie M. Rochelle, Masakazu Hirata, Tsunehisa Namba, Yukihiko Sugimoto, Atsushi Ichikawa, Shuh Narumiya, Makoto M. Taketo, Michael F Seldin

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Prostaglandins and prostacyclin are metabolites of arachidonic acid and exert a variety of actions to maintain local homeostasis in the body. Their actions are mediated by cell surface receptors specific to the respective ligands. Using a panel of interspecific backcross mice, we have mapped the prostaglandin D receptor gene (Ptgdr), prostaglandin E receptor subtype EP₁ gene (Ptgerep1), prostaglandin F receptor gene (Ptgfr), and prostacyclin receptor gene (Ptgir). Ptgdr mapped to proximal Chr 14, Ptgfr mapped to distal Chr 3, Ptgerep1 mapped to middle Chr 8, and Ptgir mapped to proximal Chr 7.

Original language	English (US)
Pages (from-to)	285-288
Number of pages	4
Journal	Genomics
Volume	32
Issue number	2
DOIs	https://doi.org/10.1006/geno.1996.0118
State	Published - Mar 1 1996
Externally published	Yes

ASJC Scopus subject areas

Genetics

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Mapping of the genes encoding mouse prostaglandin D, E, and F and prostacyclin receptors. / Ishikawa, Tomo O.; Tamai, Yoshitaka; Rochelle, Julie M.; Hirata, Masakazu; Namba, Tsunehisa; Sugimoto, Yukihiko; Ichikawa, Atsushi; Narumiya, Shuh; Taketo, Makoto M.; Seldin, Michael F.

In: Genomics, Vol. 32, No. 2, 01.03.1996, p. 285-288.

Research output: Contribution to journal › Article › peer-review

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abstract = "Prostaglandins and prostacyclin are metabolites of arachidonic acid and exert a variety of actions to maintain local homeostasis in the body. Their actions are mediated by cell surface receptors specific to the respective ligands. Using a panel of interspecific backcross mice, we have mapped the prostaglandin D receptor gene (Ptgdr), prostaglandin E receptor subtype EP1 gene (Ptgerep1), prostaglandin F receptor gene (Ptgfr), and prostacyclin receptor gene (Ptgir). Ptgdr mapped to proximal Chr 14, Ptgfr mapped to distal Chr 3, Ptgerep1 mapped to middle Chr 8, and Ptgir mapped to proximal Chr 7.",

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AU - Sugimoto, Yukihiko

AU - Ichikawa, Atsushi

AU - Narumiya, Shuh

AU - Taketo, Makoto M.

AU - Seldin, Michael F

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Mapping of the genes encoding mouse prostaglandin D, E, and F and prostacyclin receptors

Abstract

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