Abstract
Two bcl-2 alleles have been identified in inbred strains of mice by restriction fragment length polymorphism (RFLP). Analysis of a bcl-2 RFLP in a series of bilineal congenic strains (C.D2), developed as a tool for chromosomal mapping studies, revealed linkage of bcl-2 to the Idh-1/Pep-3 region of murine chromosome 1. The co-segregation of bcl-2 alleles with allelic forms of two other chromosome 1 loci, Ren-1,2 and Spna-1, in a set of back-cross progeny, positions bcl-2 7.8 cM centromeric from Ren-1,2.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 11-15 |
| Number of pages | 5 |
| Journal | Cytogenetics and Cell Genetics |
| Volume | 47 |
| Issue number | 1-2 |
| State | Published - 1988 |
| Externally published | Yes |
ASJC Scopus subject areas
- Cell Biology
- Genetics
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Cite this
Mock, B. A., Givol, D., D'Hoostelaere, L. A., Huppi, K., Seldin, M. F., Gurfinkel, N., Unger, T., Potter, M., & Mushinski, J. F. (1988). Mapping of the bcl-2 oncogene on mouse chromosome 1. Cytogenetics and Cell Genetics, 47(1-2), 11-15.