TY - JOUR
T1 - Mapping of the bcl-2 oncogene on mouse chromosome 1.
AU - Mock, B. A.
AU - Givol, D.
AU - D'Hoostelaere, L. A.
AU - Huppi, K.
AU - Seldin, Michael F
AU - Gurfinkel, N.
AU - Unger, T.
AU - Potter, M.
AU - Mushinski, J. F.
PY - 1988
Y1 - 1988
N2 - Two bcl-2 alleles have been identified in inbred strains of mice by restriction fragment length polymorphism (RFLP). Analysis of a bcl-2 RFLP in a series of bilineal congenic strains (C.D2), developed as a tool for chromosomal mapping studies, revealed linkage of bcl-2 to the Idh-1/Pep-3 region of murine chromosome 1. The co-segregation of bcl-2 alleles with allelic forms of two other chromosome 1 loci, Ren-1,2 and Spna-1, in a set of back-cross progeny, positions bcl-2 7.8 cM centromeric from Ren-1,2.
AB - Two bcl-2 alleles have been identified in inbred strains of mice by restriction fragment length polymorphism (RFLP). Analysis of a bcl-2 RFLP in a series of bilineal congenic strains (C.D2), developed as a tool for chromosomal mapping studies, revealed linkage of bcl-2 to the Idh-1/Pep-3 region of murine chromosome 1. The co-segregation of bcl-2 alleles with allelic forms of two other chromosome 1 loci, Ren-1,2 and Spna-1, in a set of back-cross progeny, positions bcl-2 7.8 cM centromeric from Ren-1,2.
UR - http://www.scopus.com/inward/record.url?scp=0023756597&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023756597&partnerID=8YFLogxK
M3 - Article
C2 - 2895697
AN - SCOPUS:0023756597
VL - 47
SP - 11
EP - 15
JO - Cytogenetic and Genome Research
JF - Cytogenetic and Genome Research
SN - 1424-8581
IS - 1-2
ER -