Mapping of the bcl-2 oncogene on mouse chromosome 1.

B. A. Mock, D. Givol, L. A. D'Hoostelaere, K. Huppi, Michael F Seldin, N. Gurfinkel, T. Unger, M. Potter, J. F. Mushinski

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Two bcl-2 alleles have been identified in inbred strains of mice by restriction fragment length polymorphism (RFLP). Analysis of a bcl-2 RFLP in a series of bilineal congenic strains (C.D2), developed as a tool for chromosomal mapping studies, revealed linkage of bcl-2 to the Idh-1/Pep-3 region of murine chromosome 1. The co-segregation of bcl-2 alleles with allelic forms of two other chromosome 1 loci, Ren-1,2 and Spna-1, in a set of back-cross progeny, positions bcl-2 7.8 cM centromeric from Ren-1,2.

Original languageEnglish (US)
Pages (from-to)11-15
Number of pages5
JournalCytogenetics and Cell Genetics
Volume47
Issue number1-2
StatePublished - 1988
Externally publishedYes

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Chromosomes, Human, Pair 1
Oncogenes
Restriction Fragment Length Polymorphisms
Alleles
Inbred Strains Mice

ASJC Scopus subject areas

  • Cell Biology
  • Genetics

Cite this

Mock, B. A., Givol, D., D'Hoostelaere, L. A., Huppi, K., Seldin, M. F., Gurfinkel, N., ... Mushinski, J. F. (1988). Mapping of the bcl-2 oncogene on mouse chromosome 1. Cytogenetics and Cell Genetics, 47(1-2), 11-15.

Mapping of the bcl-2 oncogene on mouse chromosome 1. / Mock, B. A.; Givol, D.; D'Hoostelaere, L. A.; Huppi, K.; Seldin, Michael F; Gurfinkel, N.; Unger, T.; Potter, M.; Mushinski, J. F.

In: Cytogenetics and Cell Genetics, Vol. 47, No. 1-2, 1988, p. 11-15.

Research output: Contribution to journalArticle

Mock, BA, Givol, D, D'Hoostelaere, LA, Huppi, K, Seldin, MF, Gurfinkel, N, Unger, T, Potter, M & Mushinski, JF 1988, 'Mapping of the bcl-2 oncogene on mouse chromosome 1.', Cytogenetics and Cell Genetics, vol. 47, no. 1-2, pp. 11-15.
Mock BA, Givol D, D'Hoostelaere LA, Huppi K, Seldin MF, Gurfinkel N et al. Mapping of the bcl-2 oncogene on mouse chromosome 1. Cytogenetics and Cell Genetics. 1988;47(1-2):11-15.
Mock, B. A. ; Givol, D. ; D'Hoostelaere, L. A. ; Huppi, K. ; Seldin, Michael F ; Gurfinkel, N. ; Unger, T. ; Potter, M. ; Mushinski, J. F. / Mapping of the bcl-2 oncogene on mouse chromosome 1. In: Cytogenetics and Cell Genetics. 1988 ; Vol. 47, No. 1-2. pp. 11-15.
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