Mapping of human chromosome 5 microsatellite DNA polymorphisms

James L. Weber, Mihael H. Polymeropoulos, Paula E. May, Anne E. Kwitek, Hong Xiao, John Douglas Mcpherson, John J. Wasmuth

Research output: Contribution to journalArticle

77 Citations (Scopus)

Abstract

Thirteen moderately to highly informative microsatellite DNA polymorphisms based on (dC-dA)n · (dG-dT)n repeats were mapped to segments of human chromosome 5 using both linkage analysis and a panel of somatic cell hybrids which contained rearranged chromosomes. The markers were distributed throughout most of the length of the chromosome from the regions p15.3-p15.1 to q33.3-qter. Maps of the sites of meiotic recombination within the reference families proved particularly useful for the purpose of integrating new polymorphisms into the existing linkage map.

Original languageEnglish (US)
Pages (from-to)695-700
Number of pages6
JournalGenomics
Volume11
Issue number3
DOIs
StatePublished - 1991

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Chromosomes, Human, Pair 5
Human Chromosomes
Microsatellite Repeats
Chromosomes
Hybrid Cells
DNA
Genetic Recombination

ASJC Scopus subject areas

  • Genetics

Cite this

Weber, J. L., Polymeropoulos, M. H., May, P. E., Kwitek, A. E., Xiao, H., Mcpherson, J. D., & Wasmuth, J. J. (1991). Mapping of human chromosome 5 microsatellite DNA polymorphisms. Genomics, 11(3), 695-700. https://doi.org/10.1016/0888-7543(91)90077-R

Mapping of human chromosome 5 microsatellite DNA polymorphisms. / Weber, James L.; Polymeropoulos, Mihael H.; May, Paula E.; Kwitek, Anne E.; Xiao, Hong; Mcpherson, John Douglas; Wasmuth, John J.

In: Genomics, Vol. 11, No. 3, 1991, p. 695-700.

Research output: Contribution to journalArticle

Weber, JL, Polymeropoulos, MH, May, PE, Kwitek, AE, Xiao, H, Mcpherson, JD & Wasmuth, JJ 1991, 'Mapping of human chromosome 5 microsatellite DNA polymorphisms', Genomics, vol. 11, no. 3, pp. 695-700. https://doi.org/10.1016/0888-7543(91)90077-R
Weber JL, Polymeropoulos MH, May PE, Kwitek AE, Xiao H, Mcpherson JD et al. Mapping of human chromosome 5 microsatellite DNA polymorphisms. Genomics. 1991;11(3):695-700. https://doi.org/10.1016/0888-7543(91)90077-R
Weber, James L. ; Polymeropoulos, Mihael H. ; May, Paula E. ; Kwitek, Anne E. ; Xiao, Hong ; Mcpherson, John Douglas ; Wasmuth, John J. / Mapping of human chromosome 5 microsatellite DNA polymorphisms. In: Genomics. 1991 ; Vol. 11, No. 3. pp. 695-700.
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