Mapping of Abll within a conserved linkage group on distal mouse chromosome 1 syntenic with human chromosome 1 using an interspecific cross

Michael F Seldin, Gary D. Kruh

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

A human Abelson related gene (ABLL) cDNA clone was used to detect restriction fragment length polymorphisms (RFLPs) on mouse Southern blots. Abll was mapped to mouse chromosome 1 by analysis of segregation with other distal chromosome 1 genetic polymorphisms by using a panel of DNAs from [( C3H HeJ- gld gld × Mus spretus)F1 × C3H HeJ- gld gld] interspecific backcross mice. The data indicate the following gene order: (centromere)-CD45-6.5 cM-Lamb-2-1 cM-Abll-2 cM-At-3. The results extend the analysis of a large conserved linkage group spanning nearly 30 cM on distal mouse chromosome 1 syntenic with human chromosome 1q21-32. Within this linkage group similar relative positions have been characterized in both species for C4BP, REN, CD45, LAMB2, ABLL, AT3, APOA2, and SPTA.

Original languageEnglish (US)
Pages (from-to)221-223
Number of pages3
JournalGenomics
Volume4
Issue number2
DOIs
StatePublished - 1989
Externally publishedYes

Fingerprint

Chromosomes, Human, Pair 1
Human Chromosomes
Gene Order
Centromere
Genetic Polymorphisms
Southern Blotting
Restriction Fragment Length Polymorphisms
Complementary DNA
Clone Cells
DNA
Genes

ASJC Scopus subject areas

  • Genetics

Cite this

@article{dc611fec05e64a109ff5d59b24d1f5d5,
title = "Mapping of Abll within a conserved linkage group on distal mouse chromosome 1 syntenic with human chromosome 1 using an interspecific cross",
abstract = "A human Abelson related gene (ABLL) cDNA clone was used to detect restriction fragment length polymorphisms (RFLPs) on mouse Southern blots. Abll was mapped to mouse chromosome 1 by analysis of segregation with other distal chromosome 1 genetic polymorphisms by using a panel of DNAs from [( C3H HeJ- gld gld × Mus spretus)F1 × C3H HeJ- gld gld] interspecific backcross mice. The data indicate the following gene order: (centromere)-CD45-6.5 cM-Lamb-2-1 cM-Abll-2 cM-At-3. The results extend the analysis of a large conserved linkage group spanning nearly 30 cM on distal mouse chromosome 1 syntenic with human chromosome 1q21-32. Within this linkage group similar relative positions have been characterized in both species for C4BP, REN, CD45, LAMB2, ABLL, AT3, APOA2, and SPTA.",
author = "Seldin, {Michael F} and Kruh, {Gary D.}",
year = "1989",
doi = "10.1016/0888-7543(89)90305-4",
language = "English (US)",
volume = "4",
pages = "221--223",
journal = "Genomics",
issn = "0888-7543",
publisher = "Academic Press Inc.",
number = "2",

}

TY - JOUR

T1 - Mapping of Abll within a conserved linkage group on distal mouse chromosome 1 syntenic with human chromosome 1 using an interspecific cross

AU - Seldin, Michael F

AU - Kruh, Gary D.

PY - 1989

Y1 - 1989

N2 - A human Abelson related gene (ABLL) cDNA clone was used to detect restriction fragment length polymorphisms (RFLPs) on mouse Southern blots. Abll was mapped to mouse chromosome 1 by analysis of segregation with other distal chromosome 1 genetic polymorphisms by using a panel of DNAs from [( C3H HeJ- gld gld × Mus spretus)F1 × C3H HeJ- gld gld] interspecific backcross mice. The data indicate the following gene order: (centromere)-CD45-6.5 cM-Lamb-2-1 cM-Abll-2 cM-At-3. The results extend the analysis of a large conserved linkage group spanning nearly 30 cM on distal mouse chromosome 1 syntenic with human chromosome 1q21-32. Within this linkage group similar relative positions have been characterized in both species for C4BP, REN, CD45, LAMB2, ABLL, AT3, APOA2, and SPTA.

AB - A human Abelson related gene (ABLL) cDNA clone was used to detect restriction fragment length polymorphisms (RFLPs) on mouse Southern blots. Abll was mapped to mouse chromosome 1 by analysis of segregation with other distal chromosome 1 genetic polymorphisms by using a panel of DNAs from [( C3H HeJ- gld gld × Mus spretus)F1 × C3H HeJ- gld gld] interspecific backcross mice. The data indicate the following gene order: (centromere)-CD45-6.5 cM-Lamb-2-1 cM-Abll-2 cM-At-3. The results extend the analysis of a large conserved linkage group spanning nearly 30 cM on distal mouse chromosome 1 syntenic with human chromosome 1q21-32. Within this linkage group similar relative positions have been characterized in both species for C4BP, REN, CD45, LAMB2, ABLL, AT3, APOA2, and SPTA.

UR - http://www.scopus.com/inward/record.url?scp=0024616345&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024616345&partnerID=8YFLogxK

U2 - 10.1016/0888-7543(89)90305-4

DO - 10.1016/0888-7543(89)90305-4

M3 - Article

C2 - 2567701

AN - SCOPUS:0024616345

VL - 4

SP - 221

EP - 223

JO - Genomics

JF - Genomics

SN - 0888-7543

IS - 2

ER -