Management of idiopathic thrombocytopenic purpura during pregnancy

R. K. Laros, Richard L Sweet

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Management of idiopathic thrombocytopenic purpura (ITP) during pregnancy requires concern for both fetal and maternal morbidity and death. A review of 14 pregnancies revealed significant maternal morbidity but no maternal deaths. The perinatal mortality was 21%. Current recommendations for management include: corticosteroids, splenectomy if response is unsatisfactory, liberal use of platelet transfusion if surgical intervention is required in the face of significant thrombocytopenia, and careful observation of the newborn infant and treatment with corticosteroids and/or platelets if thrombocytopenia is severe.

Original languageEnglish (US)
Pages (from-to)182-191
Number of pages10
JournalAmerican Journal of Obstetrics and Gynecology
Volume122
Issue number2
StatePublished - 1975

Fingerprint

Maternal Death
Idiopathic Thrombocytopenic Purpura
Thrombocytopenia
Adrenal Cortex Hormones
Morbidity
Pregnancy
Platelet Transfusion
Perinatal Mortality
Splenectomy
Blood Platelets
Mothers
Observation
Newborn Infant
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

Management of idiopathic thrombocytopenic purpura during pregnancy. / Laros, R. K.; Sweet, Richard L.

In: American Journal of Obstetrics and Gynecology, Vol. 122, No. 2, 1975, p. 182-191.

Research output: Contribution to journalArticle

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