Management of disseminated midgut carcinoid tumours

H. Ahlman, B. Wangberg, S. Jansson, O. Stenqvist, K. Geterud, Ulf Tylen, K. Caidahl, T. Schersten, L. E. Tisell

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Forty-one patients with disseminated midgut carcinoid tumours were treated over a 6-year period according to a strict programme including primary surgical treatment. In 10 patients, a total remission of the disease was obtained. Patients with bilobar hepatic disease had ischaemic treatment of their liver metastases by hepatic arterial embolisation after primary surgical and medical treatment (low dose octreotide). Thus, by combining surgical, radiological and medical treatment modalities, we wanted to offer these patients optimal palliation. This treatment programme resulted in good symptomatic relief in all patients accompanied by a marked reduction in 5-hydroxyindoleacetic acid (5-HIAA) levels. At recurrence of symptoms in combination with rising 5-HIAA levels, embolisation was repeated. Ten of the treated patients have deceased during the observation period, but only 5 from their carcinoid disease.

Original languageEnglish (US)
Pages (from-to)78-96
Number of pages19
JournalDigestion
Volume49
Issue number2
StatePublished - 1991
Externally publishedYes

Fingerprint

Carcinoid Tumor
Hydroxyindoleacetic Acid
Liver
Therapeutics
Octreotide
Observation
Neoplasm Metastasis
Recurrence

Keywords

  • Carcinoid tumours
  • Embolisation for carcinoid tumours
  • Midgut carcinoid tumours
  • Octreotide

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Ahlman, H., Wangberg, B., Jansson, S., Stenqvist, O., Geterud, K., Tylen, U., ... Tisell, L. E. (1991). Management of disseminated midgut carcinoid tumours. Digestion, 49(2), 78-96.

Management of disseminated midgut carcinoid tumours. / Ahlman, H.; Wangberg, B.; Jansson, S.; Stenqvist, O.; Geterud, K.; Tylen, Ulf; Caidahl, K.; Schersten, T.; Tisell, L. E.

In: Digestion, Vol. 49, No. 2, 1991, p. 78-96.

Research output: Contribution to journalArticle

Ahlman, H, Wangberg, B, Jansson, S, Stenqvist, O, Geterud, K, Tylen, U, Caidahl, K, Schersten, T & Tisell, LE 1991, 'Management of disseminated midgut carcinoid tumours', Digestion, vol. 49, no. 2, pp. 78-96.
Ahlman H, Wangberg B, Jansson S, Stenqvist O, Geterud K, Tylen U et al. Management of disseminated midgut carcinoid tumours. Digestion. 1991;49(2):78-96.
Ahlman, H. ; Wangberg, B. ; Jansson, S. ; Stenqvist, O. ; Geterud, K. ; Tylen, Ulf ; Caidahl, K. ; Schersten, T. ; Tisell, L. E. / Management of disseminated midgut carcinoid tumours. In: Digestion. 1991 ; Vol. 49, No. 2. pp. 78-96.
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