Potential complications from radiation therapy requiring supportive care measures include acute, subacute (also called early delayed), and chronic (late delayed) entities and are directly related to the site of radiation, subsequent dose, and volume of tissue exposed. Here we specifically concentrate on acute and, to a lesser extent, subacute issues. Data in children, especially of a prospective nature, are quite limited, and therefore we rely on extrapolation of data from adult studies which may or may not include pediatric patients. Studies on simple and widely utilized historical treatment strategies are often lacking; therefore, reference to clinical practice guidelines is made where possible. Radiation toxicity is examined in a site- and dosedependent fashion with a discussion of supportive care evidence to date and recom mendations on evidence-based treatment guidelines, where available.
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health