Abstract
OBJECTIVES: To compare mammographic density among premenopausal and early perimenopausal women from four racial/ethnic groups and to examine density and acculturation among Japanese and Chinese women. DESIGN: The study included 391 white, 60 African American, 171 Japanese, and 179 Chinese participants in the Study of Women's Health Across the Nation, a multisite study of US women transitioning through menopause. Mammograms done when women were premenopausal or early perimenopausal were assessed for area of dense breast tissue and the percent of the breast occupied by dense tissue (percent density). Information on race/ethnicity, acculturation, and other factors was obtained from standardized instruments. Multiple linear regression modeling was used to examine the association between race/ethnicity or acculturation and density measures. RESULTS: Age-adjusted mean percent density was highest for Chinese (52%) and lowest for African American (34%) women. After additional adjustment for body mass index, menopause status, age at first birth, breast-feeding duration, waist circumference, and smoking, African Americans had the highest mean percent density (51%) and Japanese women had the lowest (39%). In contrast, the area of dense tissue was highest for African Americans and similar for white, Japanese, and Chinese women. Less acculturated Chinese and Japanese women tended to have a larger area of density and a higher percent density. CONCLUSIONS: Neither the age-adjusted nor fully adjusted results for percent density or area of dense tissue reflected current differences in breast cancer incidence rates among similarly aged African American, Japanese, Chinese, and white women. In addition, mammographic density was higher in less acculturated Asian women.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 891-899 |
| Number of pages | 9 |
| Journal | Menopause |
| Volume | 14 |
| Issue number | 5 |
| DOIs | |
| State | Published - Sep 2007 |
| Externally published | Yes |
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Keywords
- Acculturation
- Ethnicity
- Mammographic density
- Premenopause
- Race
ASJC Scopus subject areas
- Obstetrics and Gynecology
Cite this
Mammographic density in a multiethnic cohort. / Habel, Laurel A.; Capra, Angela M.; Oestreicher, Nina; Greendale, Gail A.; Cauley, Jane A.; Bromberger, Joyce; Crandall, Carolyn J.; Gold, Ellen B; Modugno, Francesmary; Salane, Martine; Quesenberry, Charles; Sternfeld, Barbara.
In: Menopause, Vol. 14, No. 5, 09.2007, p. 891-899.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Mammographic density in a multiethnic cohort
AU - Habel, Laurel A.
AU - Capra, Angela M.
AU - Oestreicher, Nina
AU - Greendale, Gail A.
AU - Cauley, Jane A.
AU - Bromberger, Joyce
AU - Crandall, Carolyn J.
AU - Gold, Ellen B
AU - Modugno, Francesmary
AU - Salane, Martine
AU - Quesenberry, Charles
AU - Sternfeld, Barbara
PY - 2007/9
Y1 - 2007/9
N2 - OBJECTIVES: To compare mammographic density among premenopausal and early perimenopausal women from four racial/ethnic groups and to examine density and acculturation among Japanese and Chinese women. DESIGN: The study included 391 white, 60 African American, 171 Japanese, and 179 Chinese participants in the Study of Women's Health Across the Nation, a multisite study of US women transitioning through menopause. Mammograms done when women were premenopausal or early perimenopausal were assessed for area of dense breast tissue and the percent of the breast occupied by dense tissue (percent density). Information on race/ethnicity, acculturation, and other factors was obtained from standardized instruments. Multiple linear regression modeling was used to examine the association between race/ethnicity or acculturation and density measures. RESULTS: Age-adjusted mean percent density was highest for Chinese (52%) and lowest for African American (34%) women. After additional adjustment for body mass index, menopause status, age at first birth, breast-feeding duration, waist circumference, and smoking, African Americans had the highest mean percent density (51%) and Japanese women had the lowest (39%). In contrast, the area of dense tissue was highest for African Americans and similar for white, Japanese, and Chinese women. Less acculturated Chinese and Japanese women tended to have a larger area of density and a higher percent density. CONCLUSIONS: Neither the age-adjusted nor fully adjusted results for percent density or area of dense tissue reflected current differences in breast cancer incidence rates among similarly aged African American, Japanese, Chinese, and white women. In addition, mammographic density was higher in less acculturated Asian women.
AB - OBJECTIVES: To compare mammographic density among premenopausal and early perimenopausal women from four racial/ethnic groups and to examine density and acculturation among Japanese and Chinese women. DESIGN: The study included 391 white, 60 African American, 171 Japanese, and 179 Chinese participants in the Study of Women's Health Across the Nation, a multisite study of US women transitioning through menopause. Mammograms done when women were premenopausal or early perimenopausal were assessed for area of dense breast tissue and the percent of the breast occupied by dense tissue (percent density). Information on race/ethnicity, acculturation, and other factors was obtained from standardized instruments. Multiple linear regression modeling was used to examine the association between race/ethnicity or acculturation and density measures. RESULTS: Age-adjusted mean percent density was highest for Chinese (52%) and lowest for African American (34%) women. After additional adjustment for body mass index, menopause status, age at first birth, breast-feeding duration, waist circumference, and smoking, African Americans had the highest mean percent density (51%) and Japanese women had the lowest (39%). In contrast, the area of dense tissue was highest for African Americans and similar for white, Japanese, and Chinese women. Less acculturated Chinese and Japanese women tended to have a larger area of density and a higher percent density. CONCLUSIONS: Neither the age-adjusted nor fully adjusted results for percent density or area of dense tissue reflected current differences in breast cancer incidence rates among similarly aged African American, Japanese, Chinese, and white women. In addition, mammographic density was higher in less acculturated Asian women.
KW - Acculturation
KW - Ethnicity
KW - Mammographic density
KW - Premenopause
KW - Race
UR - http://www.scopus.com/inward/record.url?scp=34948866680&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34948866680&partnerID=8YFLogxK
U2 - 10.1097/gme.0b013e318032569c
DO - 10.1097/gme.0b013e318032569c
M3 - Article
C2 - 17414171
AN - SCOPUS:34948866680
VL - 14
SP - 891
EP - 899
JO - Menopause
JF - Menopause
SN - 1072-3714
IS - 5
ER -