Malignant peripheral nerve sheath tumor of the uterine cervix treated with radical vaginal trachelectomy

Anne O. Rodriguez, Alexander M. Truskinovsky, Monica Kasrazadeh, Gary S Leiserowitz

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Background. Malignant peripheral nerve sheath tumors (MPNST) are rare tumors which occur primarily in major nerve trunks and most commonly in patients with neurofibromatosis. Only seven prior cases of these tumors arising in the uterine cervix have been reported, all of which were treated by hysterectomy. Case. We report a 22-year-old woman with MPNST of the uterine cervix which recurred after loop electrocautery excision and had positive margins on cone biopsy. She was treated definitively with radical trachelectomy and is well with no sign of recurrence 20 months later. Conclusions. MPNST of the uterine cervix is a rare, but potentially aggressive neoplasm. This is the first case of such a tumor treated successfully with preservation of the patients fertility.

Original languageEnglish (US)
Pages (from-to)201-204
Number of pages4
JournalGynecologic Oncology
Volume100
Issue number1
DOIs
StatePublished - Jan 2006

Keywords

  • Malignant peripheral nerve sheath tumor
  • Malignant schwannoma
  • Radical trachelectomy
  • Uterine cervix

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Oncology

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