Maillard reaction products in purified diets induce taurine depletion in cats which is reversed by antibiotics

Seungwook W. Kim, Quinton Rogers, James Morris

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

The effects of heat processing (Maillard reaction) and addition of antibiotics to diets on the metabolism of taurine in adult cats were studied. Groups of four cats were given daily 22 g/kg body weight one of four purified diets based on casein and starch. All diets contained the same major ingredients as the control (diet 1), except for starch substitutions. Diet 2 was autoclaved; in diet 3, 50 g glucose replaced 50 g starch before autoclaving; in diet 4, only the casein component was autoclaved with 50 g glucose before addition to the diet. Diets were fed for 5 wk, then a mixture of antibiotics was added to all diets and they were fed for a further 5 wk. In the first (no antibiotics) period, cats given the Maillard reaction products (diets 3 and 4) had a significant depletion of plasma and whole blood taurine and had twice the fecal, but less than half the urinary total taurine excretion of control cats. The addition of antibiotics to the diets restored plasma and whole blood concentration in eats given diets 3 and 4, reduced fecal and increased urinary taurine excretion, and decreased fecal cholyltaurine hydrolase activity. These results suggest that Maillard reaction products promote an enteric flora that favors degradation of taurine and decreases recycling of taurine by the enterohepatic route.

Original languageEnglish (US)
Pages (from-to)195-201
Number of pages7
JournalJournal of Nutrition
Volume126
Issue number1
StatePublished - Jan 1 1996

Fingerprint

Maillard Reaction
Taurine
Cats
Anti-Bacterial Agents
Diet
Starch
choloylglycine hydrolase
Caseins
Glucose
Recycling

Keywords

  • antibiotics
  • bile acid
  • cats
  • cholyltaurine hydrolase
  • Maillard reaction products

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Maillard reaction products in purified diets induce taurine depletion in cats which is reversed by antibiotics. / Kim, Seungwook W.; Rogers, Quinton; Morris, James.

In: Journal of Nutrition, Vol. 126, No. 1, 01.01.1996, p. 195-201.

Research output: Contribution to journalArticle

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