Magnetization of large polystyrene peptide beads for capturing and expanding cancer cells

Jan Mařík, Derick H Lau, Aimin Song, Xiaobing Wang, Ruiwu Liu, Kit Lam

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

A method is described for preparation of large magnetic polystyrene beads coupled with peptide ligands for surface receptors of lung cancer cells. We have demonstrated the feasibility of using these magnetic peptide beads for capturing and enriching lung cancer cells spiked into blood. These magnetic peptide beads potentially can be used to efficiently isolate cancer cells from body fluids.

Original languageEnglish (US)
Pages (from-to)153-157
Number of pages5
JournalJournal of Magnetism and Magnetic Materials
Volume264
Issue number2-3
DOIs
StatePublished - Aug 2003

Fingerprint

Polystyrenes
beads
Peptides
peptides
Magnetization
polystyrene
cancer
Cells
lungs
magnetization
body fluids
Body fluids
blood
Blood
Ligands
preparation
ligands

Keywords

  • Cancer cell isolation
  • Magnetic peptide beads

ASJC Scopus subject areas

  • Condensed Matter Physics

Cite this

Magnetization of large polystyrene peptide beads for capturing and expanding cancer cells. / Mařík, Jan; Lau, Derick H; Song, Aimin; Wang, Xiaobing; Liu, Ruiwu; Lam, Kit.

In: Journal of Magnetism and Magnetic Materials, Vol. 264, No. 2-3, 08.2003, p. 153-157.

Research output: Contribution to journalArticle

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