Magnetization of large polystyrene peptide beads for capturing and expanding cancer cells

Jan Mařík; Derick H Lau; Aimin Song; Xiaobing Wang; Ruiwu Liu; Kit Lam

doi:10.1016/S0304-8853(03)00179-3

Magnetization of large polystyrene peptide beads for capturing and expanding cancer cells

Jan Mařík, Derick H Lau, Aimin Song, Xiaobing Wang, Ruiwu Liu, Kit Lam

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

A method is described for preparation of large magnetic polystyrene beads coupled with peptide ligands for surface receptors of lung cancer cells. We have demonstrated the feasibility of using these magnetic peptide beads for capturing and enriching lung cancer cells spiked into blood. These magnetic peptide beads potentially can be used to efficiently isolate cancer cells from body fluids.

Original language	English (US)
Pages (from-to)	153-157
Number of pages	5
Journal	Journal of Magnetism and Magnetic Materials
Volume	264
Issue number	2-3
DOIs	https://doi.org/10.1016/S0304-8853(03)00179-3
State	Published - Aug 2003

Keywords

Cancer cell isolation
Magnetic peptide beads

ASJC Scopus subject areas

Condensed Matter Physics

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10.1016/S0304-8853(03)00179-3

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title = "Magnetization of large polystyrene peptide beads for capturing and expanding cancer cells",

abstract = "A method is described for preparation of large magnetic polystyrene beads coupled with peptide ligands for surface receptors of lung cancer cells. We have demonstrated the feasibility of using these magnetic peptide beads for capturing and enriching lung cancer cells spiked into blood. These magnetic peptide beads potentially can be used to efficiently isolate cancer cells from body fluids.",

keywords = "Cancer cell isolation, Magnetic peptide beads",

author = "Jan Ma{\v r}{\'i}k and Lau, {Derick H} and Aimin Song and Xiaobing Wang and Ruiwu Liu and Kit Lam",

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AU - Mařík, Jan

AU - Lau, Derick H

AU - Song, Aimin

AU - Wang, Xiaobing

AU - Liu, Ruiwu

AU - Lam, Kit

PY - 2003/8

Y1 - 2003/8

N2 - A method is described for preparation of large magnetic polystyrene beads coupled with peptide ligands for surface receptors of lung cancer cells. We have demonstrated the feasibility of using these magnetic peptide beads for capturing and enriching lung cancer cells spiked into blood. These magnetic peptide beads potentially can be used to efficiently isolate cancer cells from body fluids.

AB - A method is described for preparation of large magnetic polystyrene beads coupled with peptide ligands for surface receptors of lung cancer cells. We have demonstrated the feasibility of using these magnetic peptide beads for capturing and enriching lung cancer cells spiked into blood. These magnetic peptide beads potentially can be used to efficiently isolate cancer cells from body fluids.

KW - Cancer cell isolation

KW - Magnetic peptide beads

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DO - 10.1016/S0304-8853(03)00179-3

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EP - 157

JO - Journal of Magnetism and Magnetic Materials

JF - Journal of Magnetism and Magnetic Materials

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