Abstract
Background: Compared with the Goutallier classification, chemical shift-based magnetic resonance (MR) fat quantification has superior reliability and accuracy in evaluation of muscle fatty infiltration. We used this method to assess the relationship between rotator cuff (RC) muscle fat fractions, tendon disease severity, and subject characteristics. Methods: In total, 182 subjects with shoulder symptoms underwent shoulder MR imaging including additional sequences for fat quantitation. Then, fat fraction maps were manually segmented, and custom software was used to compute the fat fraction. Goutallier scores were also obtained. The relationship between fat fraction and tendon tear severity and subject characteristics was assessed with descriptive statistics, analysis of variance, Student t test of different subgroups, and simple and multiple linear regression analysis. Results: Statistically higher supraspinatus fat fractions were observed in subgroups with tendon tears >3 cm, retraction >1 cm, age >50 years, body mass index (BMI) >30, higher Goutallier score, female gender, and longer symptom duration. A significant linear relationship was seen between RC fat fraction and tendon disease severity, age, and BMI but not symptom duration. Multiple regression models with fat fraction and tendon disease, age, BMI, and gender were significant for all 4 muscles (P < .001). The slope of fatty infiltration increase with age was reduced after adjustment for tendon disease, BMI, and gender. Conclusion: RC fat fraction assessed by chemical shift MR demonstrated a significant linear relationship with tendon tear severity, age, BMI, and gender but not with symptom duration.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1442-1451 |
| Number of pages | 10 |
| Journal | Journal of Shoulder and Elbow Surgery |
| Volume | 24 |
| Issue number | 9 |
| DOIs | |
| State | Published - Jan 1 2015 |
| Externally published | Yes |
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Keywords
- Diagnostic Study
- Fatty infiltration
- Level III
- MRI evaluation
- Muscle degeneration
- Rotator cuff tear
- Tear size
ASJC Scopus subject areas
- Surgery
- Orthopedics and Sports Medicine
Cite this
Magnetic resonance rotator cuff fat fraction and its relationship with tendon tear severity and subject characteristics. / Lee, Sonia; Lucas, Robert M.; Lansdown, Drew A.; Nardo, Lorenzo; Lai, Andrew; Link, Thomas M.; Krug, Roland; Ma, C. Benjamin.
In: Journal of Shoulder and Elbow Surgery, Vol. 24, No. 9, 01.01.2015, p. 1442-1451.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Magnetic resonance rotator cuff fat fraction and its relationship with tendon tear severity and subject characteristics
AU - Lee, Sonia
AU - Lucas, Robert M.
AU - Lansdown, Drew A.
AU - Nardo, Lorenzo
AU - Lai, Andrew
AU - Link, Thomas M.
AU - Krug, Roland
AU - Ma, C. Benjamin
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Background: Compared with the Goutallier classification, chemical shift-based magnetic resonance (MR) fat quantification has superior reliability and accuracy in evaluation of muscle fatty infiltration. We used this method to assess the relationship between rotator cuff (RC) muscle fat fractions, tendon disease severity, and subject characteristics. Methods: In total, 182 subjects with shoulder symptoms underwent shoulder MR imaging including additional sequences for fat quantitation. Then, fat fraction maps were manually segmented, and custom software was used to compute the fat fraction. Goutallier scores were also obtained. The relationship between fat fraction and tendon tear severity and subject characteristics was assessed with descriptive statistics, analysis of variance, Student t test of different subgroups, and simple and multiple linear regression analysis. Results: Statistically higher supraspinatus fat fractions were observed in subgroups with tendon tears >3 cm, retraction >1 cm, age >50 years, body mass index (BMI) >30, higher Goutallier score, female gender, and longer symptom duration. A significant linear relationship was seen between RC fat fraction and tendon disease severity, age, and BMI but not symptom duration. Multiple regression models with fat fraction and tendon disease, age, BMI, and gender were significant for all 4 muscles (P < .001). The slope of fatty infiltration increase with age was reduced after adjustment for tendon disease, BMI, and gender. Conclusion: RC fat fraction assessed by chemical shift MR demonstrated a significant linear relationship with tendon tear severity, age, BMI, and gender but not with symptom duration.
AB - Background: Compared with the Goutallier classification, chemical shift-based magnetic resonance (MR) fat quantification has superior reliability and accuracy in evaluation of muscle fatty infiltration. We used this method to assess the relationship between rotator cuff (RC) muscle fat fractions, tendon disease severity, and subject characteristics. Methods: In total, 182 subjects with shoulder symptoms underwent shoulder MR imaging including additional sequences for fat quantitation. Then, fat fraction maps were manually segmented, and custom software was used to compute the fat fraction. Goutallier scores were also obtained. The relationship between fat fraction and tendon tear severity and subject characteristics was assessed with descriptive statistics, analysis of variance, Student t test of different subgroups, and simple and multiple linear regression analysis. Results: Statistically higher supraspinatus fat fractions were observed in subgroups with tendon tears >3 cm, retraction >1 cm, age >50 years, body mass index (BMI) >30, higher Goutallier score, female gender, and longer symptom duration. A significant linear relationship was seen between RC fat fraction and tendon disease severity, age, and BMI but not symptom duration. Multiple regression models with fat fraction and tendon disease, age, BMI, and gender were significant for all 4 muscles (P < .001). The slope of fatty infiltration increase with age was reduced after adjustment for tendon disease, BMI, and gender. Conclusion: RC fat fraction assessed by chemical shift MR demonstrated a significant linear relationship with tendon tear severity, age, BMI, and gender but not with symptom duration.
KW - Diagnostic Study
KW - Fatty infiltration
KW - Level III
KW - MRI evaluation
KW - Muscle degeneration
KW - Rotator cuff tear
KW - Tear size
UR - http://www.scopus.com/inward/record.url?scp=84938969503&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84938969503&partnerID=8YFLogxK
U2 - 10.1016/j.jse.2015.01.013
DO - 10.1016/j.jse.2015.01.013
M3 - Article
C2 - 25819731
AN - SCOPUS:84938969503
VL - 24
SP - 1442
EP - 1451
JO - Journal of Shoulder and Elbow Surgery
JF - Journal of Shoulder and Elbow Surgery
SN - 1058-2746
IS - 9
ER -