Magnetic resonance imaging findings in Finnish Spitz dogs with focal epilepsy

Ranno Viitmaa, S. Cizinauskas, L. A. Bergamasco, E. Kuusela, Peter J Pascoe, A. M. Teppo, T. S. Jokinen, L. Kivisaari, M. Snellman

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Eleven Finnish Spitz dogs with focal seizures and 3 healthy controls were evaluated. General clinical and neurological examinations, blood examination, urinalysis, cerebrospinal fluid examination, electroencephalography (EEG), and magnetic resonance imaging (MRI) of the brain were performed on all dogs. On EEG examination, focal epileptic activity was found in 7 of 11 dogs (64%), and generalized epileptic activity was observed in 4 of 11 dogs (36%). MRI (performed with 1.5 T equipment) detected changes in 1 epileptic dog. Mild contrast enhancement after gadolinium injection was identified in this dog's right parietal cortex. However, no such changes were observed in repeated magnetic resonance images. Special emphasis was given to seizure history to determine any correlations between seizure intervals and MRI findings. Our results indicate that Finnish Spitz dogs with focal seizures suffer from focal idiopathic epilepsy and have nondetectable findings on MRI or pathology. MRI showed poor sensitivity in detecting epileptogenic areas in our patients with focal seizures. Reversible MRI changes in 1 dog could have been caused by seizures.

Original languageEnglish (US)
Pages (from-to)305-310
Number of pages6
JournalJournal of Veterinary Internal Medicine
Volume20
Issue number2
DOIs
StatePublished - Mar 2006

Fingerprint

Partial Epilepsy
epilepsy
magnetic resonance imaging
seizures
Magnetic Resonance Imaging
Dogs
Seizures
dogs
electroencephalography
Electroencephalography
gadolinium
Parietal Lobe
Urinalysis
urinalysis
Neurologic Examination
Gadolinium
cerebrospinal fluid
clinical examination
Cerebrospinal Fluid
cortex

Keywords

  • Canine
  • Idiopathic epilepsy
  • Partial seizures
  • Reversible brain changes
  • Symptomatic epilepsy

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Magnetic resonance imaging findings in Finnish Spitz dogs with focal epilepsy. / Viitmaa, Ranno; Cizinauskas, S.; Bergamasco, L. A.; Kuusela, E.; Pascoe, Peter J; Teppo, A. M.; Jokinen, T. S.; Kivisaari, L.; Snellman, M.

In: Journal of Veterinary Internal Medicine, Vol. 20, No. 2, 03.2006, p. 305-310.

Research output: Contribution to journalArticle

Viitmaa, R, Cizinauskas, S, Bergamasco, LA, Kuusela, E, Pascoe, PJ, Teppo, AM, Jokinen, TS, Kivisaari, L & Snellman, M 2006, 'Magnetic resonance imaging findings in Finnish Spitz dogs with focal epilepsy', Journal of Veterinary Internal Medicine, vol. 20, no. 2, pp. 305-310. https://doi.org/10.1892/0891-6640(2006)20[305:MRIFIF]2.0.CO;2
Viitmaa, Ranno ; Cizinauskas, S. ; Bergamasco, L. A. ; Kuusela, E. ; Pascoe, Peter J ; Teppo, A. M. ; Jokinen, T. S. ; Kivisaari, L. ; Snellman, M. / Magnetic resonance imaging findings in Finnish Spitz dogs with focal epilepsy. In: Journal of Veterinary Internal Medicine. 2006 ; Vol. 20, No. 2. pp. 305-310.
@article{0748c4504895419faf516056f28066b3,
title = "Magnetic resonance imaging findings in Finnish Spitz dogs with focal epilepsy",
abstract = "Eleven Finnish Spitz dogs with focal seizures and 3 healthy controls were evaluated. General clinical and neurological examinations, blood examination, urinalysis, cerebrospinal fluid examination, electroencephalography (EEG), and magnetic resonance imaging (MRI) of the brain were performed on all dogs. On EEG examination, focal epileptic activity was found in 7 of 11 dogs (64{\%}), and generalized epileptic activity was observed in 4 of 11 dogs (36{\%}). MRI (performed with 1.5 T equipment) detected changes in 1 epileptic dog. Mild contrast enhancement after gadolinium injection was identified in this dog's right parietal cortex. However, no such changes were observed in repeated magnetic resonance images. Special emphasis was given to seizure history to determine any correlations between seizure intervals and MRI findings. Our results indicate that Finnish Spitz dogs with focal seizures suffer from focal idiopathic epilepsy and have nondetectable findings on MRI or pathology. MRI showed poor sensitivity in detecting epileptogenic areas in our patients with focal seizures. Reversible MRI changes in 1 dog could have been caused by seizures.",
keywords = "Canine, Idiopathic epilepsy, Partial seizures, Reversible brain changes, Symptomatic epilepsy",
author = "Ranno Viitmaa and S. Cizinauskas and Bergamasco, {L. A.} and E. Kuusela and Pascoe, {Peter J} and Teppo, {A. M.} and Jokinen, {T. S.} and L. Kivisaari and M. Snellman",
year = "2006",
month = "3",
doi = "10.1892/0891-6640(2006)20[305:MRIFIF]2.0.CO;2",
language = "English (US)",
volume = "20",
pages = "305--310",
journal = "Journal of Veterinary Internal Medicine",
issn = "0891-6640",
publisher = "Wiley-Blackwell",
number = "2",

}

TY - JOUR

T1 - Magnetic resonance imaging findings in Finnish Spitz dogs with focal epilepsy

AU - Viitmaa, Ranno

AU - Cizinauskas, S.

AU - Bergamasco, L. A.

AU - Kuusela, E.

AU - Pascoe, Peter J

AU - Teppo, A. M.

AU - Jokinen, T. S.

AU - Kivisaari, L.

AU - Snellman, M.

PY - 2006/3

Y1 - 2006/3

N2 - Eleven Finnish Spitz dogs with focal seizures and 3 healthy controls were evaluated. General clinical and neurological examinations, blood examination, urinalysis, cerebrospinal fluid examination, electroencephalography (EEG), and magnetic resonance imaging (MRI) of the brain were performed on all dogs. On EEG examination, focal epileptic activity was found in 7 of 11 dogs (64%), and generalized epileptic activity was observed in 4 of 11 dogs (36%). MRI (performed with 1.5 T equipment) detected changes in 1 epileptic dog. Mild contrast enhancement after gadolinium injection was identified in this dog's right parietal cortex. However, no such changes were observed in repeated magnetic resonance images. Special emphasis was given to seizure history to determine any correlations between seizure intervals and MRI findings. Our results indicate that Finnish Spitz dogs with focal seizures suffer from focal idiopathic epilepsy and have nondetectable findings on MRI or pathology. MRI showed poor sensitivity in detecting epileptogenic areas in our patients with focal seizures. Reversible MRI changes in 1 dog could have been caused by seizures.

AB - Eleven Finnish Spitz dogs with focal seizures and 3 healthy controls were evaluated. General clinical and neurological examinations, blood examination, urinalysis, cerebrospinal fluid examination, electroencephalography (EEG), and magnetic resonance imaging (MRI) of the brain were performed on all dogs. On EEG examination, focal epileptic activity was found in 7 of 11 dogs (64%), and generalized epileptic activity was observed in 4 of 11 dogs (36%). MRI (performed with 1.5 T equipment) detected changes in 1 epileptic dog. Mild contrast enhancement after gadolinium injection was identified in this dog's right parietal cortex. However, no such changes were observed in repeated magnetic resonance images. Special emphasis was given to seizure history to determine any correlations between seizure intervals and MRI findings. Our results indicate that Finnish Spitz dogs with focal seizures suffer from focal idiopathic epilepsy and have nondetectable findings on MRI or pathology. MRI showed poor sensitivity in detecting epileptogenic areas in our patients with focal seizures. Reversible MRI changes in 1 dog could have been caused by seizures.

KW - Canine

KW - Idiopathic epilepsy

KW - Partial seizures

KW - Reversible brain changes

KW - Symptomatic epilepsy

UR - http://www.scopus.com/inward/record.url?scp=33645651294&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33645651294&partnerID=8YFLogxK

U2 - 10.1892/0891-6640(2006)20[305:MRIFIF]2.0.CO;2

DO - 10.1892/0891-6640(2006)20[305:MRIFIF]2.0.CO;2

M3 - Article

C2 - 16594587

AN - SCOPUS:33645651294

VL - 20

SP - 305

EP - 310

JO - Journal of Veterinary Internal Medicine

JF - Journal of Veterinary Internal Medicine

SN - 0891-6640

IS - 2

ER -