Magnetic resonance imaging does not define tumor boundaries.

L. D. Lunsford, A. J. Martinez, Richard E Latchaw

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

To define tumor boundaries prior to radiation therapy, 13 patients with intracranial glial neoplasms had tumor biopsies using magnetic resonance imaging (MRI)--computed tomography (CT) stereotactic technique. Precise histologic sampling of the lesion volume was correlated with the MRI and CT-defined 'lesion'. Tumor boundaries extended beyond the CT or MRI margin in 4 of 4 cases of glioblastoma, 1 of 3 cases of anaplastic astrocytoma, and 1 of 6 cases of well-differentiated astrocytoma. While stereotactic MRI is superior to stereotactic CT in the visualization of glial neoplasms, accurate tumor biopsy is mandatory to define both tumor type and margins before pre-operative radiation therapy.

Original languageEnglish (US)
Pages (from-to)154-156
Number of pages3
JournalActa Radiologica, Supplement
Volume369
StatePublished - 1986
Externally publishedYes

Fingerprint

Magnetic Resonance Imaging
Tomography
Neoplasms
Astrocytoma
Neuroglia
Radiotherapy
Stereotaxic Techniques
Biopsy
Glioblastoma
Brain Neoplasms

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Magnetic resonance imaging does not define tumor boundaries. / Lunsford, L. D.; Martinez, A. J.; Latchaw, Richard E.

In: Acta Radiologica, Supplement, Vol. 369, 1986, p. 154-156.

Research output: Contribution to journalArticle

Lunsford, L. D. ; Martinez, A. J. ; Latchaw, Richard E. / Magnetic resonance imaging does not define tumor boundaries. In: Acta Radiologica, Supplement. 1986 ; Vol. 369. pp. 154-156.
@article{71e1d385ef7f4be3a206d81132698db2,
title = "Magnetic resonance imaging does not define tumor boundaries.",
abstract = "To define tumor boundaries prior to radiation therapy, 13 patients with intracranial glial neoplasms had tumor biopsies using magnetic resonance imaging (MRI)--computed tomography (CT) stereotactic technique. Precise histologic sampling of the lesion volume was correlated with the MRI and CT-defined 'lesion'. Tumor boundaries extended beyond the CT or MRI margin in 4 of 4 cases of glioblastoma, 1 of 3 cases of anaplastic astrocytoma, and 1 of 6 cases of well-differentiated astrocytoma. While stereotactic MRI is superior to stereotactic CT in the visualization of glial neoplasms, accurate tumor biopsy is mandatory to define both tumor type and margins before pre-operative radiation therapy.",
author = "Lunsford, {L. D.} and Martinez, {A. J.} and Latchaw, {Richard E}",
year = "1986",
language = "English (US)",
volume = "369",
pages = "154--156",
journal = "Acta Radiologica, Supplement",
issn = "0365-5954",
publisher = "Blackwell Publishing",

}

TY - JOUR

T1 - Magnetic resonance imaging does not define tumor boundaries.

AU - Lunsford, L. D.

AU - Martinez, A. J.

AU - Latchaw, Richard E

PY - 1986

Y1 - 1986

N2 - To define tumor boundaries prior to radiation therapy, 13 patients with intracranial glial neoplasms had tumor biopsies using magnetic resonance imaging (MRI)--computed tomography (CT) stereotactic technique. Precise histologic sampling of the lesion volume was correlated with the MRI and CT-defined 'lesion'. Tumor boundaries extended beyond the CT or MRI margin in 4 of 4 cases of glioblastoma, 1 of 3 cases of anaplastic astrocytoma, and 1 of 6 cases of well-differentiated astrocytoma. While stereotactic MRI is superior to stereotactic CT in the visualization of glial neoplasms, accurate tumor biopsy is mandatory to define both tumor type and margins before pre-operative radiation therapy.

AB - To define tumor boundaries prior to radiation therapy, 13 patients with intracranial glial neoplasms had tumor biopsies using magnetic resonance imaging (MRI)--computed tomography (CT) stereotactic technique. Precise histologic sampling of the lesion volume was correlated with the MRI and CT-defined 'lesion'. Tumor boundaries extended beyond the CT or MRI margin in 4 of 4 cases of glioblastoma, 1 of 3 cases of anaplastic astrocytoma, and 1 of 6 cases of well-differentiated astrocytoma. While stereotactic MRI is superior to stereotactic CT in the visualization of glial neoplasms, accurate tumor biopsy is mandatory to define both tumor type and margins before pre-operative radiation therapy.

UR - http://www.scopus.com/inward/record.url?scp=0022821290&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022821290&partnerID=8YFLogxK

M3 - Article

C2 - 2980437

AN - SCOPUS:0022821290

VL - 369

SP - 154

EP - 156

JO - Acta Radiologica, Supplement

JF - Acta Radiologica, Supplement

SN - 0365-5954

ER -