Magnetic resonance imaging analysis of extremely slow flow in a model shunt system

Edmund Frank, Michael Buonocore, Larry Hein

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Shunt malfunction is common and its diagnosis may require invasive testing that may be inaccurate or result in complications. Magnetic resonance imaging (MRI) may prove to be a useful noninvasive test of shunt function as it has been shown that MRI is capable of measuring cerebrospinal fluid (CSF) flows from 2 ml/h to 40 ml/h in model systems. Since flows in functioning shunt systems can be less than 2 ml/h, MRI must be sensitive enough to detect flow in this range in order to be a valid test for shunt function. Continuing previous studies, we have studied MRI flow-related enhancement at flow rates from 0 to 2 ml/h. Multiple spin echo scans (TR2000, TE20) were made through a specialized section of tubing in a model shunt system. The intensity of the MRI signal at points known to demonstrate maximal flow-related enhancement was measured. A linear relationship was demonstrated between signal intensity and flow as low as 0.8 ml/h. These results add support to the concept that MRI is sensitive enough to detect the lowest flows present in functioning shunt systems and therefore may be useful as a noninvasive test of shunt function.

Original languageEnglish (US)
Pages (from-to)73-75
Number of pages3
JournalChild's Nervous System
Volume8
Issue number2
DOIs
StatePublished - Mar 1992

Fingerprint

Magnetic Resonance Imaging
Cerebrospinal Fluid

Keywords

  • Cerebrospinal fluid
  • Cerebrospinal fluid shunt
  • Magnetic resonance imaging
  • Shunt malfunction

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

Cite this

Magnetic resonance imaging analysis of extremely slow flow in a model shunt system. / Frank, Edmund; Buonocore, Michael; Hein, Larry.

In: Child's Nervous System, Vol. 8, No. 2, 03.1992, p. 73-75.

Research output: Contribution to journalArticle

Frank, Edmund ; Buonocore, Michael ; Hein, Larry. / Magnetic resonance imaging analysis of extremely slow flow in a model shunt system. In: Child's Nervous System. 1992 ; Vol. 8, No. 2. pp. 73-75.
@article{f0a7b56be1b74e84bfdbd360851373bd,
title = "Magnetic resonance imaging analysis of extremely slow flow in a model shunt system",
abstract = "Shunt malfunction is common and its diagnosis may require invasive testing that may be inaccurate or result in complications. Magnetic resonance imaging (MRI) may prove to be a useful noninvasive test of shunt function as it has been shown that MRI is capable of measuring cerebrospinal fluid (CSF) flows from 2 ml/h to 40 ml/h in model systems. Since flows in functioning shunt systems can be less than 2 ml/h, MRI must be sensitive enough to detect flow in this range in order to be a valid test for shunt function. Continuing previous studies, we have studied MRI flow-related enhancement at flow rates from 0 to 2 ml/h. Multiple spin echo scans (TR2000, TE20) were made through a specialized section of tubing in a model shunt system. The intensity of the MRI signal at points known to demonstrate maximal flow-related enhancement was measured. A linear relationship was demonstrated between signal intensity and flow as low as 0.8 ml/h. These results add support to the concept that MRI is sensitive enough to detect the lowest flows present in functioning shunt systems and therefore may be useful as a noninvasive test of shunt function.",
keywords = "Cerebrospinal fluid, Cerebrospinal fluid shunt, Magnetic resonance imaging, Shunt malfunction",
author = "Edmund Frank and Michael Buonocore and Larry Hein",
year = "1992",
month = "3",
doi = "10.1007/BF00298443",
language = "English (US)",
volume = "8",
pages = "73--75",
journal = "Child's Nervous System",
issn = "0256-7040",
publisher = "Springer Verlag",
number = "2",

}

TY - JOUR

T1 - Magnetic resonance imaging analysis of extremely slow flow in a model shunt system

AU - Frank, Edmund

AU - Buonocore, Michael

AU - Hein, Larry

PY - 1992/3

Y1 - 1992/3

N2 - Shunt malfunction is common and its diagnosis may require invasive testing that may be inaccurate or result in complications. Magnetic resonance imaging (MRI) may prove to be a useful noninvasive test of shunt function as it has been shown that MRI is capable of measuring cerebrospinal fluid (CSF) flows from 2 ml/h to 40 ml/h in model systems. Since flows in functioning shunt systems can be less than 2 ml/h, MRI must be sensitive enough to detect flow in this range in order to be a valid test for shunt function. Continuing previous studies, we have studied MRI flow-related enhancement at flow rates from 0 to 2 ml/h. Multiple spin echo scans (TR2000, TE20) were made through a specialized section of tubing in a model shunt system. The intensity of the MRI signal at points known to demonstrate maximal flow-related enhancement was measured. A linear relationship was demonstrated between signal intensity and flow as low as 0.8 ml/h. These results add support to the concept that MRI is sensitive enough to detect the lowest flows present in functioning shunt systems and therefore may be useful as a noninvasive test of shunt function.

AB - Shunt malfunction is common and its diagnosis may require invasive testing that may be inaccurate or result in complications. Magnetic resonance imaging (MRI) may prove to be a useful noninvasive test of shunt function as it has been shown that MRI is capable of measuring cerebrospinal fluid (CSF) flows from 2 ml/h to 40 ml/h in model systems. Since flows in functioning shunt systems can be less than 2 ml/h, MRI must be sensitive enough to detect flow in this range in order to be a valid test for shunt function. Continuing previous studies, we have studied MRI flow-related enhancement at flow rates from 0 to 2 ml/h. Multiple spin echo scans (TR2000, TE20) were made through a specialized section of tubing in a model shunt system. The intensity of the MRI signal at points known to demonstrate maximal flow-related enhancement was measured. A linear relationship was demonstrated between signal intensity and flow as low as 0.8 ml/h. These results add support to the concept that MRI is sensitive enough to detect the lowest flows present in functioning shunt systems and therefore may be useful as a noninvasive test of shunt function.

KW - Cerebrospinal fluid

KW - Cerebrospinal fluid shunt

KW - Magnetic resonance imaging

KW - Shunt malfunction

UR - http://www.scopus.com/inward/record.url?scp=0026513403&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026513403&partnerID=8YFLogxK

U2 - 10.1007/BF00298443

DO - 10.1007/BF00298443

M3 - Article

C2 - 1591749

AN - SCOPUS:0026513403

VL - 8

SP - 73

EP - 75

JO - Child's Nervous System

JF - Child's Nervous System

SN - 0256-7040

IS - 2

ER -