Magnetic field exposure and long-term survival among children with leukaemia

D. E. Foliart, Bradley H Pollock, G. Mezei, R. Iriye, J. M. Silva, K. L. Ebi, L. Kheifets, M. P. Link, R. Kavet

Research output: Contribution to journalArticle

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Abstract

We examined the association between magnetic field (MF) exposure and survival among children with acute lymphoblastic leukaemia (ALL) treated at 51 Pediatric Oncology Group centres between 1996 and 2001. Of 1672 potentially eligible children under treatment, 482 (29%) participated and personal 24-h MF measurements were obtained from 412 participants. A total of 386 children with ALL and 361 with B-precursor ALL were included in the analysis of event-free survival (time from diagnosis to first treatment failure, relapse, secondary malignancy, or death) and overall survival. After adjustment for risk group and socioeconomic status, the event-free survival hazard ratio (HR) for children with measurements ≥0.3 μT was 1.9 (95% confidence interval (CI) 0.8, 4.9), compared to <0.1 μT. For survival, elevated HRs were found for children exposed to ≥0.3 μT (multivariate HR = 4.5, 95% CI 1.5-13.8) but based on only four deaths among 19 children. While risk was increased among children with exposures above 0.3 μT, the small numbers limited inferences for this finding.

Original languageEnglish (US)
Pages (from-to)161-164
Number of pages4
JournalBritish Journal of Cancer
Volume94
Issue number1
DOIs
StatePublished - Jan 16 2006
Externally publishedYes

Fingerprint

Magnetic Fields
Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Disease-Free Survival
Confidence Intervals
Risk Adjustment
Treatment Failure
Social Class
Pediatrics
Recurrence
Neoplasms

Keywords

  • Acute childhood leukaemia
  • Electromagnetic fields
  • Leukaemia
  • Lymphoblastic leukaemia

ASJC Scopus subject areas

  • Medicine(all)
  • Oncology
  • Cancer Research

Cite this

Foliart, D. E., Pollock, B. H., Mezei, G., Iriye, R., Silva, J. M., Ebi, K. L., ... Kavet, R. (2006). Magnetic field exposure and long-term survival among children with leukaemia. British Journal of Cancer, 94(1), 161-164. https://doi.org/10.1038/sj.bjc.6602916

Magnetic field exposure and long-term survival among children with leukaemia. / Foliart, D. E.; Pollock, Bradley H; Mezei, G.; Iriye, R.; Silva, J. M.; Ebi, K. L.; Kheifets, L.; Link, M. P.; Kavet, R.

In: British Journal of Cancer, Vol. 94, No. 1, 16.01.2006, p. 161-164.

Research output: Contribution to journalArticle

Foliart, DE, Pollock, BH, Mezei, G, Iriye, R, Silva, JM, Ebi, KL, Kheifets, L, Link, MP & Kavet, R 2006, 'Magnetic field exposure and long-term survival among children with leukaemia', British Journal of Cancer, vol. 94, no. 1, pp. 161-164. https://doi.org/10.1038/sj.bjc.6602916
Foliart, D. E. ; Pollock, Bradley H ; Mezei, G. ; Iriye, R. ; Silva, J. M. ; Ebi, K. L. ; Kheifets, L. ; Link, M. P. ; Kavet, R. / Magnetic field exposure and long-term survival among children with leukaemia. In: British Journal of Cancer. 2006 ; Vol. 94, No. 1. pp. 161-164.
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