Macromolecular crystallization in a high throughput setting

George T. DeTitta; Melissa A. Bianca; Robert J. Collins; Ann Marie E. Faust; Jillian N. Kaczmarek; Joseph R. Luft; Nancy A. Fehrman; Walter A. Pangborn; Jeffrey M. Salerno; Jennifer R. Wolfley; Igor Jurisica; Patrick Rogers; Gerald Quon; Janice Glasgow; Suzanne Fortier

Macromolecular crystallization in a high throughput setting

George T. DeTitta, Melissa A. Bianca, Robert J. Collins, Ann Marie E. Faust, Jillian N. Kaczmarek, Joseph R. Luft, Nancy A. Fehrman, Walter A. Pangborn, Jeffrey M. Salerno, Jennifer R. Wolfley, Igor Jurisica, Patrick Rogers, Gerald Quon, Janice Glasgow, Suzanne Fortier

Research output: Contribution to conference › Paper › peer-review

2 Scopus citations

Abstract

Macromolecular crystallization has been identified as the rate-limiting step in the structural biology field. With the advent of genomic-wide approaches to structural biology, efforts to streamline and automate the process of crystal growth are mandatory. In the last eighteen months we have developed a high throughput laboratory capable of executing a million crystallization experiments a year. We will describe the efforts and comment on the first 717,312 crystal growth experiments.

Original language	English (US)
State	Published - Dec 1 2001
Externally published	Yes
Event	2001 Conference and Exhibit on International Space Station Utilization - Cape Canaveral, FL, United States Duration: Oct 15 2001 → Oct 18 2001

Other

Other	2001 Conference and Exhibit on International Space Station Utilization
Country	United States
City	Cape Canaveral, FL
Period	10/15/01 → 10/18/01

ASJC Scopus subject areas

Space and Planetary Science
Electrical and Electronic Engineering

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DeTitta, G. T., Bianca, M. A., Collins, R. J., Faust, A. M. E., Kaczmarek, J. N., Luft, J. R., Fehrman, N. A., Pangborn, W. A., Salerno, J. M., Wolfley, J. R., Jurisica, I., Rogers, P., Quon, G., Glasgow, J., & Fortier, S. (2001). Macromolecular crystallization in a high throughput setting. Paper presented at 2001 Conference and Exhibit on International Space Station Utilization, Cape Canaveral, FL, United States.

Macromolecular crystallization in a high throughput setting. / DeTitta, George T.; Bianca, Melissa A.; Collins, Robert J.; Faust, Ann Marie E.; Kaczmarek, Jillian N.; Luft, Joseph R.; Fehrman, Nancy A.; Pangborn, Walter A.; Salerno, Jeffrey M.; Wolfley, Jennifer R.; Jurisica, Igor; Rogers, Patrick; Quon, Gerald; Glasgow, Janice; Fortier, Suzanne.

2001. Paper presented at 2001 Conference and Exhibit on International Space Station Utilization, Cape Canaveral, FL, United States.

Research output: Contribution to conference › Paper › peer-review

DeTitta, GT, Bianca, MA, Collins, RJ, Faust, AME, Kaczmarek, JN, Luft, JR, Fehrman, NA, Pangborn, WA, Salerno, JM, Wolfley, JR, Jurisica, I, Rogers, P, Quon, G, Glasgow, J & Fortier, S 2001, 'Macromolecular crystallization in a high throughput setting', Paper presented at 2001 Conference and Exhibit on International Space Station Utilization, Cape Canaveral, FL, United States, 10/15/01 - 10/18/01.

DeTitta, George T. ; Bianca, Melissa A. ; Collins, Robert J. ; Faust, Ann Marie E. ; Kaczmarek, Jillian N. ; Luft, Joseph R. ; Fehrman, Nancy A. ; Pangborn, Walter A. ; Salerno, Jeffrey M. ; Wolfley, Jennifer R. ; Jurisica, Igor ; Rogers, Patrick ; Quon, Gerald ; Glasgow, Janice ; Fortier, Suzanne. / Macromolecular crystallization in a high throughput setting. Paper presented at 2001 Conference and Exhibit on International Space Station Utilization, Cape Canaveral, FL, United States.

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author = "DeTitta, {George T.} and Bianca, {Melissa A.} and Collins, {Robert J.} and Faust, {Ann Marie E.} and Kaczmarek, {Jillian N.} and Luft, {Joseph R.} and Fehrman, {Nancy A.} and Pangborn, {Walter A.} and Salerno, {Jeffrey M.} and Wolfley, {Jennifer R.} and Igor Jurisica and Patrick Rogers and Gerald Quon and Janice Glasgow and Suzanne Fortier",

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AU - DeTitta, George T.

AU - Bianca, Melissa A.

AU - Collins, Robert J.

AU - Faust, Ann Marie E.

AU - Kaczmarek, Jillian N.

AU - Luft, Joseph R.

AU - Fehrman, Nancy A.

AU - Pangborn, Walter A.

AU - Salerno, Jeffrey M.

AU - Wolfley, Jennifer R.

AU - Jurisica, Igor

AU - Rogers, Patrick

AU - Quon, Gerald

AU - Glasgow, Janice

AU - Fortier, Suzanne

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N2 - Macromolecular crystallization has been identified as the rate-limiting step in the structural biology field. With the advent of genomic-wide approaches to structural biology, efforts to streamline and automate the process of crystal growth are mandatory. In the last eighteen months we have developed a high throughput laboratory capable of executing a million crystallization experiments a year. We will describe the efforts and comment on the first 717,312 crystal growth experiments.

AB - Macromolecular crystallization has been identified as the rate-limiting step in the structural biology field. With the advent of genomic-wide approaches to structural biology, efforts to streamline and automate the process of crystal growth are mandatory. In the last eighteen months we have developed a high throughput laboratory capable of executing a million crystallization experiments a year. We will describe the efforts and comment on the first 717,312 crystal growth experiments.

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T2 - 2001 Conference and Exhibit on International Space Station Utilization

Y2 - 15 October 2001 through 18 October 2001

ER -

Macromolecular crystallization in a high throughput setting

Abstract

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ASJC Scopus subject areas

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