Macromolecular crystallization in a high throughput setting

George T. DeTitta, Melissa A. Bianca, Robert J. Collins, Ann Marie E. Faust, Jillian N. Kaczmarek, Joseph R. Luft, Nancy A. Fehrman, Walter A. Pangborn, Jeffrey M. Salerno, Jennifer R. Wolfley, Igor Jurisica, Patrick Rogers, Gerald Quon, Janice Glasgow, Suzanne Fortier

Research output: Contribution to conferencePaper

2 Citations (Scopus)

Abstract

Macromolecular crystallization has been identified as the rate-limiting step in the structural biology field. With the advent of genomic-wide approaches to structural biology, efforts to streamline and automate the process of crystal growth are mandatory. In the last eighteen months we have developed a high throughput laboratory capable of executing a million crystallization experiments a year. We will describe the efforts and comment on the first 717,312 crystal growth experiments.

Original languageEnglish (US)
StatePublished - Dec 1 2001
Externally publishedYes
Event2001 Conference and Exhibit on International Space Station Utilization - Cape Canaveral, FL, United States
Duration: Oct 15 2001Oct 18 2001

Other

Other2001 Conference and Exhibit on International Space Station Utilization
CountryUnited States
CityCape Canaveral, FL
Period10/15/0110/18/01

Fingerprint

biology
Crystal growth
crystal growth
crystallization
Crystallization
Throughput
crystal
genomics
experiment
Experiments
laboratory
rate

ASJC Scopus subject areas

  • Space and Planetary Science
  • Electrical and Electronic Engineering

Cite this

DeTitta, G. T., Bianca, M. A., Collins, R. J., Faust, A. M. E., Kaczmarek, J. N., Luft, J. R., ... Fortier, S. (2001). Macromolecular crystallization in a high throughput setting. Paper presented at 2001 Conference and Exhibit on International Space Station Utilization, Cape Canaveral, FL, United States.

Macromolecular crystallization in a high throughput setting. / DeTitta, George T.; Bianca, Melissa A.; Collins, Robert J.; Faust, Ann Marie E.; Kaczmarek, Jillian N.; Luft, Joseph R.; Fehrman, Nancy A.; Pangborn, Walter A.; Salerno, Jeffrey M.; Wolfley, Jennifer R.; Jurisica, Igor; Rogers, Patrick; Quon, Gerald; Glasgow, Janice; Fortier, Suzanne.

2001. Paper presented at 2001 Conference and Exhibit on International Space Station Utilization, Cape Canaveral, FL, United States.

Research output: Contribution to conferencePaper

DeTitta, GT, Bianca, MA, Collins, RJ, Faust, AME, Kaczmarek, JN, Luft, JR, Fehrman, NA, Pangborn, WA, Salerno, JM, Wolfley, JR, Jurisica, I, Rogers, P, Quon, G, Glasgow, J & Fortier, S 2001, 'Macromolecular crystallization in a high throughput setting' Paper presented at 2001 Conference and Exhibit on International Space Station Utilization, Cape Canaveral, FL, United States, 10/15/01 - 10/18/01, .
DeTitta GT, Bianca MA, Collins RJ, Faust AME, Kaczmarek JN, Luft JR et al. Macromolecular crystallization in a high throughput setting. 2001. Paper presented at 2001 Conference and Exhibit on International Space Station Utilization, Cape Canaveral, FL, United States.
DeTitta, George T. ; Bianca, Melissa A. ; Collins, Robert J. ; Faust, Ann Marie E. ; Kaczmarek, Jillian N. ; Luft, Joseph R. ; Fehrman, Nancy A. ; Pangborn, Walter A. ; Salerno, Jeffrey M. ; Wolfley, Jennifer R. ; Jurisica, Igor ; Rogers, Patrick ; Quon, Gerald ; Glasgow, Janice ; Fortier, Suzanne. / Macromolecular crystallization in a high throughput setting. Paper presented at 2001 Conference and Exhibit on International Space Station Utilization, Cape Canaveral, FL, United States.
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AU - Luft, Joseph R.

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