Lymphangiosarcoma in a young dog

J. E. Sagartz, Michael Dale Lairmore, D. Haines, S. E. Sheafor, C. G. Couto

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Lymphangiosarcoma was diagnosed from biopsy material obtained from an 8-week-old puppy with a progressively enlarging subcutaneous inguinal swelling. Histologically, the tumor was composed of endothelial cells immediately adjacent to large collagen bundles. Tumor cells formed irregular vascular channels which extended along the connective tissue investments of small vessels and nerves of the subcutis and deep dermis. Similar neoplastic tissue extensively infiltrated an inguinal lymph node. Neoplastic cells were immunohistochemically stained for factor 8-related antigen and were weakly positive when compared with several hemangiomas and hemangiosarcomas. Transmission electron microscopy revealed numerous micropinocytotic vesicles and a continuous basal lamina. The puppy was euthanatized at 8 months of age due to severe septic polyarthritis. Lymphangiosarcoma was documented at the site of the original tumor as well as in the axillary lymph node at necropsy.

Original languageEnglish (US)
Pages (from-to)353-356
Number of pages4
JournalVeterinary Pathology
Volume33
Issue number3
StatePublished - May 1996
Externally publishedYes

Fingerprint

Lymphangiosarcoma
puppies
lymph nodes
Groin
Dogs
hemangioma
hemangiosarcoma
neoplasms
dogs
dermis
laminae (animals)
arthritis
Lymph Nodes
blood vessels
connective tissues
endothelial cells
transmission electron microscopy
collagen
biopsy
necropsy

Keywords

  • Dogs
  • Lymphangiosarcoma
  • Neoplasia

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Sagartz, J. E., Lairmore, M. D., Haines, D., Sheafor, S. E., & Couto, C. G. (1996). Lymphangiosarcoma in a young dog. Veterinary Pathology, 33(3), 353-356.

Lymphangiosarcoma in a young dog. / Sagartz, J. E.; Lairmore, Michael Dale; Haines, D.; Sheafor, S. E.; Couto, C. G.

In: Veterinary Pathology, Vol. 33, No. 3, 05.1996, p. 353-356.

Research output: Contribution to journalArticle

Sagartz, JE, Lairmore, MD, Haines, D, Sheafor, SE & Couto, CG 1996, 'Lymphangiosarcoma in a young dog', Veterinary Pathology, vol. 33, no. 3, pp. 353-356.
Sagartz JE, Lairmore MD, Haines D, Sheafor SE, Couto CG. Lymphangiosarcoma in a young dog. Veterinary Pathology. 1996 May;33(3):353-356.
Sagartz, J. E. ; Lairmore, Michael Dale ; Haines, D. ; Sheafor, S. E. ; Couto, C. G. / Lymphangiosarcoma in a young dog. In: Veterinary Pathology. 1996 ; Vol. 33, No. 3. pp. 353-356.
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