Lupus erythematosus and localized scleroderma coexistent at the same sites: A rare presentation of overlap syndrome of connective-tissue diseases

Anabella Pascucci, Peter J. Lynch, Nasim Fazel

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Overlap syndromes are known to occur with connective-tissue diseases (CTDs). Rarely, the overlap occurs at the same tissue site. We report the case of a patient with clinical and histopathologic findings consistent with the presence of discoid lupus erythematosus (DLE) and localized scleroderma within the same lesions. Based on our case and other reported cases in the literature, the following features are common in patients with an overlap of lupus erythematosus (LE) and localized scleroderma: predilection for young women, photodistributed lesions, DLE, linear morphology clinically, and positivity along the dermoepidermal junction on direct immunofluorescence. Most patients showed good response to antimalarials, topical steroids, or systemic steroids.

Original languageEnglish (US)
Pages (from-to)359-363
Number of pages5
JournalCutis
Volume97
Issue number5
StatePublished - 2016

ASJC Scopus subject areas

  • Medicine(all)
  • Dermatology

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