Lumbar myelography with iohexol and metrizamide. A comparative multicenter prospective study.

S. A. Kieffer; E. F. Binet; D. O. Davis; T. O. Gabrielsen; D. K. Kido; Richard E Latchaw; P. A. Turski; D. D. Shaw

Lumbar myelography with iohexol and metrizamide. A comparative multicenter prospective study.

S. A. Kieffer, E. F. Binet, D. O. Davis, T. O. Gabrielsen, D. K. Kido, Richard E Latchaw, P. A. Turski, D. D. Shaw

Research output: Contribution to journal › Article › peer-review

Abstract

Diagnostic quality and adverse reactions associated with metrizamide and iohexol as contrast agents for lumbar myelography were compared in a prospective randomized double-blind study in 350 patients at seven centers. Both contrast media were administered in comparable volumes at a concentration of 180 mg I/ml. Overall quality of radiographic visualization was graded as "good" or "excellent" in 95% of 175 metrizamide studies and in 98% of 175 iohexol myelograms. Ninety-three patients examined with metrizamide (53%) and 130 patients studied with iohexol (74%) experienced no discomfort during or after myelography. The incidence of postmyelographic headache was 38% with metrizamide and 21% with iohexol. Nausea and vomiting were also more common with metrizamide. Five patients examined with metrizamide (3%) experienced transient confusion and disorientation after lumbar myelography. No such reactions were observed after iohexol myelography.

Original language	English (US)
Journal	Investigative Radiology
Volume	20
Issue number	1 Suppl
State	Published - Jan 1985
Externally published	Yes

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Radiological and Ultrasound Technology

Fingerprint Dive into the research topics of 'Lumbar myelography with iohexol and metrizamide. A comparative multicenter prospective study.'. Together they form a unique fingerprint.

Cite this

@article{bd6c6dbdf03642b3b53d584b8e38bb3f,

title = "Lumbar myelography with iohexol and metrizamide. A comparative multicenter prospective study.",

abstract = "Diagnostic quality and adverse reactions associated with metrizamide and iohexol as contrast agents for lumbar myelography were compared in a prospective randomized double-blind study in 350 patients at seven centers. Both contrast media were administered in comparable volumes at a concentration of 180 mg I/ml. Overall quality of radiographic visualization was graded as {"}good{"} or {"}excellent{"} in 95% of 175 metrizamide studies and in 98% of 175 iohexol myelograms. Ninety-three patients examined with metrizamide (53%) and 130 patients studied with iohexol (74%) experienced no discomfort during or after myelography. The incidence of postmyelographic headache was 38% with metrizamide and 21% with iohexol. Nausea and vomiting were also more common with metrizamide. Five patients examined with metrizamide (3%) experienced transient confusion and disorientation after lumbar myelography. No such reactions were observed after iohexol myelography.",

author = "Kieffer, {S. A.} and Binet, {E. F.} and Davis, {D. O.} and Gabrielsen, {T. O.} and Kido, {D. K.} and Latchaw, {Richard E} and Turski, {P. A.} and Shaw, {D. D.}",

year = "1985",

month = jan,

language = "English (US)",

volume = "20",

journal = "Investigative Radiology",

issn = "0020-9996",

publisher = "Lippincott Williams and Wilkins",

number = "1 Suppl",

}

TY - JOUR

T1 - Lumbar myelography with iohexol and metrizamide. A comparative multicenter prospective study.

AU - Kieffer, S. A.

AU - Binet, E. F.

AU - Davis, D. O.

AU - Gabrielsen, T. O.

AU - Kido, D. K.

AU - Latchaw, Richard E

AU - Turski, P. A.

AU - Shaw, D. D.

PY - 1985/1

Y1 - 1985/1

N2 - Diagnostic quality and adverse reactions associated with metrizamide and iohexol as contrast agents for lumbar myelography were compared in a prospective randomized double-blind study in 350 patients at seven centers. Both contrast media were administered in comparable volumes at a concentration of 180 mg I/ml. Overall quality of radiographic visualization was graded as "good" or "excellent" in 95% of 175 metrizamide studies and in 98% of 175 iohexol myelograms. Ninety-three patients examined with metrizamide (53%) and 130 patients studied with iohexol (74%) experienced no discomfort during or after myelography. The incidence of postmyelographic headache was 38% with metrizamide and 21% with iohexol. Nausea and vomiting were also more common with metrizamide. Five patients examined with metrizamide (3%) experienced transient confusion and disorientation after lumbar myelography. No such reactions were observed after iohexol myelography.

AB - Diagnostic quality and adverse reactions associated with metrizamide and iohexol as contrast agents for lumbar myelography were compared in a prospective randomized double-blind study in 350 patients at seven centers. Both contrast media were administered in comparable volumes at a concentration of 180 mg I/ml. Overall quality of radiographic visualization was graded as "good" or "excellent" in 95% of 175 metrizamide studies and in 98% of 175 iohexol myelograms. Ninety-three patients examined with metrizamide (53%) and 130 patients studied with iohexol (74%) experienced no discomfort during or after myelography. The incidence of postmyelographic headache was 38% with metrizamide and 21% with iohexol. Nausea and vomiting were also more common with metrizamide. Five patients examined with metrizamide (3%) experienced transient confusion and disorientation after lumbar myelography. No such reactions were observed after iohexol myelography.

UR - http://www.scopus.com/inward/record.url?scp=0021906340&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021906340&partnerID=8YFLogxK

M3 - Article

C2 - 3882614

AN - SCOPUS:0021906340

VL - 20

JO - Investigative Radiology

JF - Investigative Radiology

SN - 0020-9996

IS - 1 Suppl

ER -

Lumbar myelography with iohexol and metrizamide. A comparative multicenter prospective study.

Abstract

ASJC Scopus subject areas

Other files and links

Cite this