LTP: GluN2B on the go

Lucas Matt; Johannes W Hell

doi:10.1002/embj.201487958

LTP: GluN2B on the go

Lucas Matt, Johannes W Hell

Pharmacology

Research output: Contribution to journal › Article › peer-review

Abstract

LTP, the lasting increase in synaptic transmission following heightened activity, is viewed as the physiological basis of learning. In this issue of The EMBO Journal, Dupuis et al find that certain NMDARs diffuse away upon LTP. Antibodies against the NMDAR from patients with autoimmune synaptic encephalitis prevent this redistribution and LTP. Lateral diffusion of neuronal NMDA receptors is important for synaptic long-term potentiation and may be affected in autoimmune disorders.

Original language	English (US)
Pages (from-to)	781-782
Number of pages	2
Journal	EMBO Journal
Volume	33
Issue number	8
DOIs	https://doi.org/10.1002/embj.201487958
State	Published - Apr 16 2014

ASJC Scopus subject areas

Molecular Biology
Biochemistry, Genetics and Molecular Biology(all)
Immunology and Microbiology(all)
Neuroscience(all)

Access to Document

10.1002/embj.201487958

Cite this

@article{ae3c27abcefd4ce7a6ad7f173e0f8c3d,

title = "LTP: GluN2B on the go",

abstract = "LTP, the lasting increase in synaptic transmission following heightened activity, is viewed as the physiological basis of learning. In this issue of The EMBO Journal, Dupuis et al find that certain NMDARs diffuse away upon LTP. Antibodies against the NMDAR from patients with autoimmune synaptic encephalitis prevent this redistribution and LTP. Lateral diffusion of neuronal NMDA receptors is important for synaptic long-term potentiation and may be affected in autoimmune disorders.",

author = "Lucas Matt and Hell, {Johannes W}",

year = "2014",

month = apr,

day = "16",

doi = "10.1002/embj.201487958",

language = "English (US)",

volume = "33",

pages = "781--782",

journal = "EMBO Journal",

issn = "0261-4189",

publisher = "Nature Publishing Group",

number = "8",

}

TY - JOUR

T1 - LTP

T2 - GluN2B on the go

AU - Matt, Lucas

AU - Hell, Johannes W

PY - 2014/4/16

Y1 - 2014/4/16

N2 - LTP, the lasting increase in synaptic transmission following heightened activity, is viewed as the physiological basis of learning. In this issue of The EMBO Journal, Dupuis et al find that certain NMDARs diffuse away upon LTP. Antibodies against the NMDAR from patients with autoimmune synaptic encephalitis prevent this redistribution and LTP. Lateral diffusion of neuronal NMDA receptors is important for synaptic long-term potentiation and may be affected in autoimmune disorders.

AB - LTP, the lasting increase in synaptic transmission following heightened activity, is viewed as the physiological basis of learning. In this issue of The EMBO Journal, Dupuis et al find that certain NMDARs diffuse away upon LTP. Antibodies against the NMDAR from patients with autoimmune synaptic encephalitis prevent this redistribution and LTP. Lateral diffusion of neuronal NMDA receptors is important for synaptic long-term potentiation and may be affected in autoimmune disorders.

UR - http://www.scopus.com/inward/record.url?scp=84898878544&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84898878544&partnerID=8YFLogxK

U2 - 10.1002/embj.201487958

DO - 10.1002/embj.201487958

M3 - Article

C2 - 24599308

AN - SCOPUS:84898878544

VL - 33

SP - 781

EP - 782

JO - EMBO Journal

JF - EMBO Journal

SN - 0261-4189

IS - 8

ER -

LTP: GluN2B on the go

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this