Low-grade fibromyxoid sarcoma of the sigmoid colon

Alejandro S. Mendoza; Michael P. O'Leary; Shi Kaung Peng; Beverley A. Petrie; Andrew I. Li; Samuel W. French

doi:10.1016/j.yexmp.2015.02.007

Low-grade fibromyxoid sarcoma of the sigmoid colon

Alejandro S. Mendoza, Michael P. O'Leary, Shi Kaung Peng, Beverley A. Petrie, Andrew I. Li, Samuel W. French

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Low-grade fibromyxoid sarcoma (LGFMS) is a rare soft tissue tumor with a slight male predominance. The tumor has a tendency to arise from deep soft tissue of the trunk and lower extremities. Rare cases are reported to arise from the mediastinal and retroperitoneal areas. Its deceptively bland histologic appearance makes this tumor difficult to diagnose. Also, there are several histologic mimics that may hinder in its diagnosis. We report a case of low-grade fibromyxoid sarcoma from a 48-year-old woman, first documented herein to arise from the sigmoid. We also report the value of CD99, BCL2 and MUC4 stains in the diagnosis of this tumor.

Original language	English (US)
Pages (from-to)	300-303
Number of pages	4
Journal	Experimental and Molecular Pathology
Volume	98
Issue number	2
DOIs	https://doi.org/10.1016/j.yexmp.2015.02.007
State	Published - Apr 1 2015
Externally published	Yes

Keywords

BCL2
CD99
Low-grade fibromyxoid sarcoma
MUC4
Sigmoid

ASJC Scopus subject areas

Pathology and Forensic Medicine
Molecular Biology
Clinical Biochemistry

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10.1016/j.yexmp.2015.02.007

Cite this

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title = "Low-grade fibromyxoid sarcoma of the sigmoid colon",

abstract = "Low-grade fibromyxoid sarcoma (LGFMS) is a rare soft tissue tumor with a slight male predominance. The tumor has a tendency to arise from deep soft tissue of the trunk and lower extremities. Rare cases are reported to arise from the mediastinal and retroperitoneal areas. Its deceptively bland histologic appearance makes this tumor difficult to diagnose. Also, there are several histologic mimics that may hinder in its diagnosis. We report a case of low-grade fibromyxoid sarcoma from a 48-year-old woman, first documented herein to arise from the sigmoid. We also report the value of CD99, BCL2 and MUC4 stains in the diagnosis of this tumor.",

keywords = "BCL2, CD99, Low-grade fibromyxoid sarcoma, MUC4, Sigmoid",

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T1 - Low-grade fibromyxoid sarcoma of the sigmoid colon

AU - Mendoza, Alejandro S.

AU - O'Leary, Michael P.

AU - Peng, Shi Kaung

AU - Petrie, Beverley A.

AU - Li, Andrew I.

AU - French, Samuel W.

PY - 2015/4/1

Y1 - 2015/4/1

N2 - Low-grade fibromyxoid sarcoma (LGFMS) is a rare soft tissue tumor with a slight male predominance. The tumor has a tendency to arise from deep soft tissue of the trunk and lower extremities. Rare cases are reported to arise from the mediastinal and retroperitoneal areas. Its deceptively bland histologic appearance makes this tumor difficult to diagnose. Also, there are several histologic mimics that may hinder in its diagnosis. We report a case of low-grade fibromyxoid sarcoma from a 48-year-old woman, first documented herein to arise from the sigmoid. We also report the value of CD99, BCL2 and MUC4 stains in the diagnosis of this tumor.

AB - Low-grade fibromyxoid sarcoma (LGFMS) is a rare soft tissue tumor with a slight male predominance. The tumor has a tendency to arise from deep soft tissue of the trunk and lower extremities. Rare cases are reported to arise from the mediastinal and retroperitoneal areas. Its deceptively bland histologic appearance makes this tumor difficult to diagnose. Also, there are several histologic mimics that may hinder in its diagnosis. We report a case of low-grade fibromyxoid sarcoma from a 48-year-old woman, first documented herein to arise from the sigmoid. We also report the value of CD99, BCL2 and MUC4 stains in the diagnosis of this tumor.

KW - BCL2

KW - CD99

KW - Low-grade fibromyxoid sarcoma

KW - MUC4

KW - Sigmoid

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Low-grade fibromyxoid sarcoma of the sigmoid colon

Abstract

Keywords

ASJC Scopus subject areas

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