Abstract
Objective: To determine a rational approach to heparin dosing for thromboembolism prophylaxis. Design: Literature review. Results: Three commonly used heparin dosing regimens were identified: (1) standard low-dose heparin (5000 U administered subcutaneously 2-3 times per day); (2) adjusted- dose heparin (adequate to elevate the activated partial thromboplastin time to 5 seconds above the upper limit of normal); and (3) low-molecular-weight heparin (30 mg subcutaneously twice daily without monitoring). Conclusions: Adjusted-dose heparin thromboembolism prophylaxis is both the safest and most reliable method currently available.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1069-1073 |
| Number of pages | 5 |
| Journal | Archives of Surgery |
| Volume | 131 |
| Issue number | 10 |
| State | Published - Oct 1996 |
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ASJC Scopus subject areas
- Surgery
Cite this
Low-dose heparin thromboembolism prophylaxis. / Owings, John T; Blaisdell, F. William.
In: Archives of Surgery, Vol. 131, No. 10, 10.1996, p. 1069-1073.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Low-dose heparin thromboembolism prophylaxis
AU - Owings, John T
AU - Blaisdell, F. William
PY - 1996/10
Y1 - 1996/10
N2 - Objective: To determine a rational approach to heparin dosing for thromboembolism prophylaxis. Design: Literature review. Results: Three commonly used heparin dosing regimens were identified: (1) standard low-dose heparin (5000 U administered subcutaneously 2-3 times per day); (2) adjusted- dose heparin (adequate to elevate the activated partial thromboplastin time to 5 seconds above the upper limit of normal); and (3) low-molecular-weight heparin (30 mg subcutaneously twice daily without monitoring). Conclusions: Adjusted-dose heparin thromboembolism prophylaxis is both the safest and most reliable method currently available.
AB - Objective: To determine a rational approach to heparin dosing for thromboembolism prophylaxis. Design: Literature review. Results: Three commonly used heparin dosing regimens were identified: (1) standard low-dose heparin (5000 U administered subcutaneously 2-3 times per day); (2) adjusted- dose heparin (adequate to elevate the activated partial thromboplastin time to 5 seconds above the upper limit of normal); and (3) low-molecular-weight heparin (30 mg subcutaneously twice daily without monitoring). Conclusions: Adjusted-dose heparin thromboembolism prophylaxis is both the safest and most reliable method currently available.
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M3 - Article
C2 - 8857904
AN - SCOPUS:0029818743
VL - 131
SP - 1069
EP - 1073
JO - JAMA Surgery
JF - JAMA Surgery
SN - 2168-6254
IS - 10
ER -