Abstract
Objective: To determine a rational approach to heparin dosing for thromboembolism prophylaxis. Design: Literature review. Results: Three commonly used heparin dosing regimens were identified: (1) standard low-dose heparin (5000 U administered subcutaneously 2-3 times per day); (2) adjusted- dose heparin (adequate to elevate the activated partial thromboplastin time to 5 seconds above the upper limit of normal); and (3) low-molecular-weight heparin (30 mg subcutaneously twice daily without monitoring). Conclusions: Adjusted-dose heparin thromboembolism prophylaxis is both the safest and most reliable method currently available.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1069-1073 |
| Number of pages | 5 |
| Journal | Archives of Surgery |
| Volume | 131 |
| Issue number | 10 |
| State | Published - Oct 1996 |
ASJC Scopus subject areas
- Surgery
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Owings, J. T., & Blaisdell, F. W. (1996). Low-dose heparin thromboembolism prophylaxis. Archives of Surgery, 131(10), 1069-1073.