Abstract
Objective: To determine a rational approach to heparin dosing for thromboembolism prophylaxis. Design: Literature review. Results: Three commonly used heparin dosing regimens were identified: (1) standard low-dose heparin (5000 U administered subcutaneously 2-3 times per day); (2) adjusted- dose heparin (adequate to elevate the activated partial thromboplastin time to 5 seconds above the upper limit of normal); and (3) low-molecular-weight heparin (30 mg subcutaneously twice daily without monitoring). Conclusions: Adjusted-dose heparin thromboembolism prophylaxis is both the safest and most reliable method currently available.
Original language | English (US) |
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Pages (from-to) | 1069-1073 |
Number of pages | 5 |
Journal | Archives of Surgery |
Volume | 131 |
Issue number | 10 |
State | Published - Oct 1996 |
ASJC Scopus subject areas
- Surgery