Abstract
There is much ambiguity surrounding the diagnosis of nerve sheath tumors, including atypical neurofibroma and low-grade MPNST, and yet, the distinction between these entities designates either benign or malignant behavior and thus carries presumed profound prognostic importance that often guides treatment. This study reviews the diagnostic criteria used to designate atypical neurofibroma from low-grade MPNSTs and reviews existing literature the natural history of each of these tumors to see if the distinction is, in fact, of importance.
Original language | English (US) |
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Pages (from-to) | 519-528 |
Number of pages | 10 |
Journal | Cancers |
Volume | 5 |
Issue number | 2 |
DOIs | |
State | Published - Jun 1 2013 |
Externally published | Yes |
Keywords
- Atypical neurofibroma
- Low grade MPNST
- MPNST
- Nerve sheath tumor
- Neurofibromatosis
ASJC Scopus subject areas
- Oncology
- Cancer Research