Lost in translation: Ambiguity in nerve sheath tumor nomenclature and its resultant treatment effect

Nicholas M. Bernthal, Kevin B. Jones, Michael J. Monument, Ting Liu, David Viskochil, R Randall

Research output: Contribution to journalReview article

5 Scopus citations

Abstract

There is much ambiguity surrounding the diagnosis of nerve sheath tumors, including atypical neurofibroma and low-grade MPNST, and yet, the distinction between these entities designates either benign or malignant behavior and thus carries presumed profound prognostic importance that often guides treatment. This study reviews the diagnostic criteria used to designate atypical neurofibroma from low-grade MPNSTs and reviews existing literature the natural history of each of these tumors to see if the distinction is, in fact, of importance.

Original languageEnglish (US)
Pages (from-to)519-528
Number of pages10
JournalCancers
Volume5
Issue number2
DOIs
StatePublished - Jun 1 2013
Externally publishedYes

Keywords

  • Atypical neurofibroma
  • Low grade MPNST
  • MPNST
  • Nerve sheath tumor
  • Neurofibromatosis

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'Lost in translation: Ambiguity in nerve sheath tumor nomenclature and its resultant treatment effect'. Together they form a unique fingerprint.

  • Cite this