Abstract
There is much ambiguity surrounding the diagnosis of nerve sheath tumors, including atypical neurofibroma and low-grade MPNST, and yet, the distinction between these entities designates either benign or malignant behavior and thus carries presumed profound prognostic importance that often guides treatment. This study reviews the diagnostic criteria used to designate atypical neurofibroma from low-grade MPNSTs and reviews existing literature the natural history of each of these tumors to see if the distinction is, in fact, of importance.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 519-528 |
| Number of pages | 10 |
| Journal | Cancers |
| Volume | 5 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jun 1 2013 |
| Externally published | Yes |
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Keywords
- Atypical neurofibroma
- Low grade MPNST
- MPNST
- Nerve sheath tumor
- Neurofibromatosis
ASJC Scopus subject areas
- Oncology
- Cancer Research
Cite this
Lost in translation : Ambiguity in nerve sheath tumor nomenclature and its resultant treatment effect. / Bernthal, Nicholas M.; Jones, Kevin B.; Monument, Michael J.; Liu, Ting; Viskochil, David; Randall, R.
In: Cancers, Vol. 5, No. 2, 01.06.2013, p. 519-528.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Lost in translation
T2 - Ambiguity in nerve sheath tumor nomenclature and its resultant treatment effect
AU - Bernthal, Nicholas M.
AU - Jones, Kevin B.
AU - Monument, Michael J.
AU - Liu, Ting
AU - Viskochil, David
AU - Randall, R
PY - 2013/6/1
Y1 - 2013/6/1
N2 - There is much ambiguity surrounding the diagnosis of nerve sheath tumors, including atypical neurofibroma and low-grade MPNST, and yet, the distinction between these entities designates either benign or malignant behavior and thus carries presumed profound prognostic importance that often guides treatment. This study reviews the diagnostic criteria used to designate atypical neurofibroma from low-grade MPNSTs and reviews existing literature the natural history of each of these tumors to see if the distinction is, in fact, of importance.
AB - There is much ambiguity surrounding the diagnosis of nerve sheath tumors, including atypical neurofibroma and low-grade MPNST, and yet, the distinction between these entities designates either benign or malignant behavior and thus carries presumed profound prognostic importance that often guides treatment. This study reviews the diagnostic criteria used to designate atypical neurofibroma from low-grade MPNSTs and reviews existing literature the natural history of each of these tumors to see if the distinction is, in fact, of importance.
KW - Atypical neurofibroma
KW - Low grade MPNST
KW - MPNST
KW - Nerve sheath tumor
KW - Neurofibromatosis
UR - http://www.scopus.com/inward/record.url?scp=84878185587&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84878185587&partnerID=8YFLogxK
U2 - 10.3390/cancers5020519
DO - 10.3390/cancers5020519
M3 - Review article
C2 - 24216989
AN - SCOPUS:84878185587
VL - 5
SP - 519
EP - 528
JO - Cancers
JF - Cancers
SN - 2072-6694
IS - 2
ER -