Abstract
Different lymphoid-cell populations have been shown to interact in various immunological responses. A lymphoid-cell population that is capable of suppressing humoral and cellular immunity has been demonstrated. It is proposed that suppressor cells normally regulate continued lymphoid hyperplasia in response to various stimuli. In the absence of suppressor function, unregulated proliferation would ultimately lead to lymphoreticular malignancy. According to this mechanism, restoration of suppressor cells might prevent the development of lymphoreticular malignancies.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1174-1176 |
| Number of pages | 3 |
| Journal | The Lancet |
| Volume | 302 |
| Issue number | 7839 |
| DOIs | |
| State | Published - Nov 24 1973 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
LOSS OF SUPPRESSOR FUNCTION AS A CAUSE OF LYMPHOID MALIGNANCY. / Gershwin, M. Eric; Steinberg, AlfredD.
In: The Lancet, Vol. 302, No. 7839, 24.11.1973, p. 1174-1176.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - LOSS OF SUPPRESSOR FUNCTION AS A CAUSE OF LYMPHOID MALIGNANCY
AU - Gershwin, M. Eric
AU - Steinberg, AlfredD
PY - 1973/11/24
Y1 - 1973/11/24
N2 - Different lymphoid-cell populations have been shown to interact in various immunological responses. A lymphoid-cell population that is capable of suppressing humoral and cellular immunity has been demonstrated. It is proposed that suppressor cells normally regulate continued lymphoid hyperplasia in response to various stimuli. In the absence of suppressor function, unregulated proliferation would ultimately lead to lymphoreticular malignancy. According to this mechanism, restoration of suppressor cells might prevent the development of lymphoreticular malignancies.
AB - Different lymphoid-cell populations have been shown to interact in various immunological responses. A lymphoid-cell population that is capable of suppressing humoral and cellular immunity has been demonstrated. It is proposed that suppressor cells normally regulate continued lymphoid hyperplasia in response to various stimuli. In the absence of suppressor function, unregulated proliferation would ultimately lead to lymphoreticular malignancy. According to this mechanism, restoration of suppressor cells might prevent the development of lymphoreticular malignancies.
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UR - http://www.scopus.com/inward/citedby.url?scp=0015897871&partnerID=8YFLogxK
U2 - 10.1016/S0140-6736(73)92940-1
DO - 10.1016/S0140-6736(73)92940-1
M3 - Article
C2 - 4127550
AN - SCOPUS:0015897871
VL - 302
SP - 1174
EP - 1176
JO - The Lancet
JF - The Lancet
SN - 0140-6736
IS - 7839
ER -