Loosening of the total knee arthroplasty: Detection by radionuclide bone scanning

J. C. Hunter, R. S. Hattner, W. R. Murray, H. K. Genant

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Pain after total knee arthroplasty is a common clinical problem in orthopedics, and prosthetic loosening, often requiring surgical revision, is usually the etiology. Since standard clinical and radiographic diagnostic measures have not proven totally satisfactory, a study of the utility of bone scintigraphy to assess stability of the knee prosthesis was done. Thirty-five patients with 39 prostheses were studied. Seventeen patients with 21 total knee arthroplasties served as controls and were asymptomatic, were stable at surgery, or improved with conservative management. Eighteen knees in 18 symptomatic patients composed the experimental group. Of these, 11 knees were loose at surgery and seven have had surgery recommended. Scintigrams of the knees were obtained using 99mTc-MDP, and ranked 0-3 corresponding to increasingly abnormal localization by three observers. Highly significant differences were observed between the abnormal and control groups (p

Original languageEnglish (US)
Pages (from-to)131-136
Number of pages6
JournalAmerican Journal of Roentgenology
Issue number1
StatePublished - 1980

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


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