Abstract
Generalized linear mixed models were used to examine longitudinal trajectories of everyday functional limitations by diagnostic stability/progression. Older adults (N = 384) were followed an average 3.6 years; participants were grouped by diagnosis at study baseline and last follow-up (normal cognition, Mild Cognitive Impairment, or dementia at each time point). At study baseline there were clear group differences; most notably among participants initially characterized as cognitively normal, those who developed Mild Cognitive Impairment or dementia over follow-up already demonstrated greater functional impairment compared with those who remained cognitively normal. Change in functional impairment progressed slowly in the early disease groups, but showed an accelerated worsening in those converting to dementia.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1070-1075 |
| Number of pages | 6 |
| Journal | Psychology and Aging |
| Volume | 28 |
| Issue number | 4 |
| DOIs | |
| State | Published - Dec 2013 |
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Keywords
- Activities of daily living
- Aging
- Cognition
- Dementia
- Everyday function
- Mild Cognitive Impairment
ASJC Scopus subject areas
- Aging
- Geriatrics and Gerontology
- Social Psychology
Cite this
Longitudinal trajectories of everyday function by diagnostic status. / Tomaszewski Farias, Sarah E; Chou, Elizabeth; Harvey, Danielle J; Mungas, Dan M; Reed, Bruce R; DeCarli, Charles; Park, Lovingly Quitania; Beckett, Laurel A.
In: Psychology and Aging, Vol. 28, No. 4, 12.2013, p. 1070-1075.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Longitudinal trajectories of everyday function by diagnostic status
AU - Tomaszewski Farias, Sarah E
AU - Chou, Elizabeth
AU - Harvey, Danielle J
AU - Mungas, Dan M
AU - Reed, Bruce R
AU - DeCarli, Charles
AU - Park, Lovingly Quitania
AU - Beckett, Laurel A
PY - 2013/12
Y1 - 2013/12
N2 - Generalized linear mixed models were used to examine longitudinal trajectories of everyday functional limitations by diagnostic stability/progression. Older adults (N = 384) were followed an average 3.6 years; participants were grouped by diagnosis at study baseline and last follow-up (normal cognition, Mild Cognitive Impairment, or dementia at each time point). At study baseline there were clear group differences; most notably among participants initially characterized as cognitively normal, those who developed Mild Cognitive Impairment or dementia over follow-up already demonstrated greater functional impairment compared with those who remained cognitively normal. Change in functional impairment progressed slowly in the early disease groups, but showed an accelerated worsening in those converting to dementia.
AB - Generalized linear mixed models were used to examine longitudinal trajectories of everyday functional limitations by diagnostic stability/progression. Older adults (N = 384) were followed an average 3.6 years; participants were grouped by diagnosis at study baseline and last follow-up (normal cognition, Mild Cognitive Impairment, or dementia at each time point). At study baseline there were clear group differences; most notably among participants initially characterized as cognitively normal, those who developed Mild Cognitive Impairment or dementia over follow-up already demonstrated greater functional impairment compared with those who remained cognitively normal. Change in functional impairment progressed slowly in the early disease groups, but showed an accelerated worsening in those converting to dementia.
KW - Activities of daily living
KW - Aging
KW - Cognition
KW - Dementia
KW - Everyday function
KW - Mild Cognitive Impairment
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UR - http://www.scopus.com/inward/citedby.url?scp=84891120977&partnerID=8YFLogxK
U2 - 10.1037/a0034069
DO - 10.1037/a0034069
M3 - Article
VL - 28
SP - 1070
EP - 1075
JO - Psychology and Aging
JF - Psychology and Aging
SN - 0882-7974
IS - 4
ER -