Longitudinal changes in blood metabolites, amino acid profile, and oxidative stress markers in american foxhounds fed a nutrient-fortified diet

Alison N. Beloshapka, Maria R.C. De Godoy, Rebecca A. Carter, Andrea J Fascetti, Zengshou Yu, Bridgett J. McIntosh, Kelly S. Swanson, Preston R. Buff

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The objective of the present study was to evaluate the changes in blood metabolites, AA profile, and oxidative stress markers in American Foxhound dogs fed a nutrient-fortified endurance diet while undergoing unstructured endurance exercise over several months. Thirty-six adult American Foxhound dogs (mean age: 4.5, range 2 to 10 yr and mean BW: 34.7, range: 23.1 to 46.9 kg) were selected to participate in the study. Prior to the study, all dogs consumed a commercial diet for 16 wk. After collecting baseline blood samples, dogs were assigned to a standard commercial performance diet (control) or a nutrient-fortified dog food (test). Dogs were balanced by gender, age, body weight, and athletic performance between diets. During the study, dogs underwent 78 bouts of exercise, with approximately 22 km/bout. Blood samples were collected after 40, 75, 138, and 201 d on study (October 2012 to March 2013). All blood metabolites were similar at baseline and serum chemistry profile remained within normal ranges throughout the study. Over time, plasma taurine and vitamin E concentrations decreased (P < 0.05) in dogs fed the control diet but were maintained or increased (P < 0.05) in dogs fed the treatment diet. Also, plasma creatinine and triglycerides were lower (P < 0.05) and blood phosphorus and alkaline phosphatase were higher (P < 0.05) in dogs fed the treatment diet. Vitamin E and taurine status of dogs appear to be affected by extended endurance exercise. These data suggest dogs undergoing endurance exercise may benefit from supplementation of vitamin E and taurine to minimize oxidation and maintain taurine status.

Original languageEnglish (US)
Pages (from-to)930-940
Number of pages11
JournalJournal of Animal Science
Volume96
Issue number3
DOIs
StatePublished - Apr 3 2018

Fingerprint

Oxidative Stress
oxidative stress
Dogs
metabolites
Diet
Amino Acids
Food
amino acids
dogs
blood
nutrients
diet
taurine
Taurine
exercise
Vitamin E
vitamin E
athletic performance
pet foods
Fortified Food

Keywords

  • Canine
  • Exercise
  • Longitudinal
  • Nutrition
  • Oxidative stress

ASJC Scopus subject areas

  • Food Science
  • Animal Science and Zoology
  • Genetics

Cite this

Longitudinal changes in blood metabolites, amino acid profile, and oxidative stress markers in american foxhounds fed a nutrient-fortified diet. / Beloshapka, Alison N.; De Godoy, Maria R.C.; Carter, Rebecca A.; Fascetti, Andrea J; Yu, Zengshou; McIntosh, Bridgett J.; Swanson, Kelly S.; Buff, Preston R.

In: Journal of Animal Science, Vol. 96, No. 3, 03.04.2018, p. 930-940.

Research output: Contribution to journalArticle

Beloshapka, Alison N. ; De Godoy, Maria R.C. ; Carter, Rebecca A. ; Fascetti, Andrea J ; Yu, Zengshou ; McIntosh, Bridgett J. ; Swanson, Kelly S. ; Buff, Preston R. / Longitudinal changes in blood metabolites, amino acid profile, and oxidative stress markers in american foxhounds fed a nutrient-fortified diet. In: Journal of Animal Science. 2018 ; Vol. 96, No. 3. pp. 930-940.
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AB - The objective of the present study was to evaluate the changes in blood metabolites, AA profile, and oxidative stress markers in American Foxhound dogs fed a nutrient-fortified endurance diet while undergoing unstructured endurance exercise over several months. Thirty-six adult American Foxhound dogs (mean age: 4.5, range 2 to 10 yr and mean BW: 34.7, range: 23.1 to 46.9 kg) were selected to participate in the study. Prior to the study, all dogs consumed a commercial diet for 16 wk. After collecting baseline blood samples, dogs were assigned to a standard commercial performance diet (control) or a nutrient-fortified dog food (test). Dogs were balanced by gender, age, body weight, and athletic performance between diets. During the study, dogs underwent 78 bouts of exercise, with approximately 22 km/bout. Blood samples were collected after 40, 75, 138, and 201 d on study (October 2012 to March 2013). All blood metabolites were similar at baseline and serum chemistry profile remained within normal ranges throughout the study. Over time, plasma taurine and vitamin E concentrations decreased (P < 0.05) in dogs fed the control diet but were maintained or increased (P < 0.05) in dogs fed the treatment diet. Also, plasma creatinine and triglycerides were lower (P < 0.05) and blood phosphorus and alkaline phosphatase were higher (P < 0.05) in dogs fed the treatment diet. Vitamin E and taurine status of dogs appear to be affected by extended endurance exercise. These data suggest dogs undergoing endurance exercise may benefit from supplementation of vitamin E and taurine to minimize oxidation and maintain taurine status.

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