Abstract
Objective: To report long-term clinical outcome in dogs treated for single congenital extrahepatic portosystemic shunt (CEHPSS) with a ameroid ring constrictor (ARC) and to identify perioperative variables associated with outcome. Study Design: Retrospective, multi-institutional study. Animals: Dogs (n=206) with CEHPSS. Methods: Medical records of dogs with CEHPSS treated by ARC were reviewed for perioperative and short-term (<1 month) data. Long-term follow-up information was obtained by telephone interview with referring veterinarians and/or owners. Kaplan-Meier analysis was used to estimate median survival time. Factors associated with short-term survival, outcome grade, and total survival time were identified. Results: Fifteen dogs died <1 month after ARC placement. Follow-up data were obtained for 112 of 191 dogs that survived >1 month; median follow was 54 months (range, 1-175 months) and 103 (92%) dogs had no clinical signs. Estimated median survival time was 152 months. Variables significantly associated with short-term survival included being intact and a low total white blood cell (WBC) count. Variables significantly associated with a successful outcome included having surgery later in the study period and negative postoperative nuclear scintigraphy. In the long-term survival analyses, intact dogs and those with higher WBC counts and occlusion pressures and lower bile acid concentrations were more likely to survive. Conclusions: Dogs with CEHPSS treated by ARC generally have a good prognosis and prolonged postoperative survival.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 951-957 |
| Number of pages | 7 |
| Journal | Veterinary Surgery |
| Volume | 42 |
| Issue number | 8 |
| DOIs | |
| State | Published - Nov 2013 |
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- veterinary(all)
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Long-term outcome after surgical ameroid ring constrictor placement for treatment of single extrahepatic portosystemic shunts in dogs. / Falls, Emily L.; Milovancev, Milan; Hunt, Geraldine B; Daniel, Leticia; Mehl, Margo L.; Schmiedt, Chad W.
In: Veterinary Surgery, Vol. 42, No. 8, 11.2013, p. 951-957.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Long-term outcome after surgical ameroid ring constrictor placement for treatment of single extrahepatic portosystemic shunts in dogs
AU - Falls, Emily L.
AU - Milovancev, Milan
AU - Hunt, Geraldine B
AU - Daniel, Leticia
AU - Mehl, Margo L.
AU - Schmiedt, Chad W.
PY - 2013/11
Y1 - 2013/11
N2 - Objective: To report long-term clinical outcome in dogs treated for single congenital extrahepatic portosystemic shunt (CEHPSS) with a ameroid ring constrictor (ARC) and to identify perioperative variables associated with outcome. Study Design: Retrospective, multi-institutional study. Animals: Dogs (n=206) with CEHPSS. Methods: Medical records of dogs with CEHPSS treated by ARC were reviewed for perioperative and short-term (<1 month) data. Long-term follow-up information was obtained by telephone interview with referring veterinarians and/or owners. Kaplan-Meier analysis was used to estimate median survival time. Factors associated with short-term survival, outcome grade, and total survival time were identified. Results: Fifteen dogs died <1 month after ARC placement. Follow-up data were obtained for 112 of 191 dogs that survived >1 month; median follow was 54 months (range, 1-175 months) and 103 (92%) dogs had no clinical signs. Estimated median survival time was 152 months. Variables significantly associated with short-term survival included being intact and a low total white blood cell (WBC) count. Variables significantly associated with a successful outcome included having surgery later in the study period and negative postoperative nuclear scintigraphy. In the long-term survival analyses, intact dogs and those with higher WBC counts and occlusion pressures and lower bile acid concentrations were more likely to survive. Conclusions: Dogs with CEHPSS treated by ARC generally have a good prognosis and prolonged postoperative survival.
AB - Objective: To report long-term clinical outcome in dogs treated for single congenital extrahepatic portosystemic shunt (CEHPSS) with a ameroid ring constrictor (ARC) and to identify perioperative variables associated with outcome. Study Design: Retrospective, multi-institutional study. Animals: Dogs (n=206) with CEHPSS. Methods: Medical records of dogs with CEHPSS treated by ARC were reviewed for perioperative and short-term (<1 month) data. Long-term follow-up information was obtained by telephone interview with referring veterinarians and/or owners. Kaplan-Meier analysis was used to estimate median survival time. Factors associated with short-term survival, outcome grade, and total survival time were identified. Results: Fifteen dogs died <1 month after ARC placement. Follow-up data were obtained for 112 of 191 dogs that survived >1 month; median follow was 54 months (range, 1-175 months) and 103 (92%) dogs had no clinical signs. Estimated median survival time was 152 months. Variables significantly associated with short-term survival included being intact and a low total white blood cell (WBC) count. Variables significantly associated with a successful outcome included having surgery later in the study period and negative postoperative nuclear scintigraphy. In the long-term survival analyses, intact dogs and those with higher WBC counts and occlusion pressures and lower bile acid concentrations were more likely to survive. Conclusions: Dogs with CEHPSS treated by ARC generally have a good prognosis and prolonged postoperative survival.
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U2 - 10.1111/j.1532-950X.2013.12072.x
DO - 10.1111/j.1532-950X.2013.12072.x
M3 - Article
VL - 42
SP - 951
EP - 957
JO - Veterinary Surgery
JF - Veterinary Surgery
SN - 0161-3499
IS - 8
ER -