Long anterior zonules and pigment dispersion

Sayoko E. Moroi, Kurt K. Lark, Paul A. Sieving, Kouros Nouri-Mahdavi, Ursula Schlötzer-Schrehardt, Gregory J. Katz, Robert Ritch

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


PURPOSE: To describe pigment dispersion associated with long anterior zonules. DESIGN: Multicenter observational case series. METHODS: Fifteen patients, seven of whom were treated for glaucoma or ocular hypertension, were identified with long anterior zonules and pigment dispersion. Transmission electron microscopy was performed on one anterior capsule specimen. RESULTS: All patients had anterior zonules that inserted centrally on the lens capsule. Signs of pigment dispersion included corneal endothelial pigmentation, loss of the pupillary ruff, and variable trabecular meshwork pigmentation. Ultrasound biomicroscopy verified the lack of posterior iris insertion and concavity. There was no exfoliation material. Transmission electron microscopy showed zonular lamellae with adherent pigment granules, and no exfoliation material. CONCLUSIONS: Long anterior zonules inserted onto the central lens capsule may cause mechanical disruption of the pigment epithelium at the pupillary ruff and central iris leading to pigment dispersion.

Original languageEnglish (US)
Pages (from-to)1176-1178
Number of pages3
JournalAmerican Journal of Ophthalmology
Issue number6
StatePublished - Dec 2003
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology


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