Localization of Murine Macrophage Inducible Nitric Oxide Synthase to Mouse Chromosome 11

Margarete Mehrabian, Yu Rong Xia, Ping Zi Wen, Craig H Warden, Harvey R. Herschman, Aldons J. Lusis

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

There are at least three distinct nitric oxide (NO) synthase genes. Brain and endothelial NO synthases are constitutively synthesized, while NO synthase is inducible by cytokines in macropbages. We have utilized a backcross of (C57BL/6J × Mus spretus) × C57BL/6J to map the inducible NO synthase (Nos2). We report the chromosomal mapping of Nos2 to mouse chromosome 11, 3.3cM proximal to Scya2.

Original languageEnglish (US)
Pages (from-to)646-647
Number of pages2
JournalGenomics
Volume22
Issue number3
DOIs
StatePublished - Aug 1994

ASJC Scopus subject areas

  • Genetics

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    Mehrabian, M., Xia, Y. R., Wen, P. Z., Warden, C. H., Herschman, H. R., & Lusis, A. J. (1994). Localization of Murine Macrophage Inducible Nitric Oxide Synthase to Mouse Chromosome 11. Genomics, 22(3), 646-647. https://doi.org/10.1006/geno.1994.1441