Localization of growth arrest-specific genes on mouse Chromosomes 1, 7, 8, 11, 13, and 16

Mario P. Colombo, Alessia Martinotti, Thad A. Howard, Claudio Schneider, Peter D'Eustachio, Michael F Seldin

Research output: Contribution to journalArticle

31 Scopus citations

Abstract

Growth arrest in NIH3T3 cells is associated with increased expression of a variety of mRNAs, several of which have been isolated as cDNA clones. Six of these growth arrest-specific (Gas) genes were mapped by following the inheritance of DNA restriction fragment length variants (RFLVs) associated with them in panels of recombinant inbred (RI) strains of mice and in the progeny of backcrosses both between laboratory mouse strains and between a laboratory strain and Mus spretus. The six genes are unlinked. Gas-1 maps to Chromosome (Chr) 13, Gas-2 to Chr 7, Gas-3 to Chr 11, Gas-4 to Chr 16, Gas-6 to Chr 8, and Gas-10 to Chr 1.

Original languageEnglish (US)
Pages (from-to)130-134
Number of pages5
JournalMammalian Genome
Volume2
Issue number2
DOIs
StatePublished - Jun 1992
Externally publishedYes

ASJC Scopus subject areas

  • Genetics

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    Colombo, M. P., Martinotti, A., Howard, T. A., Schneider, C., D'Eustachio, P., & Seldin, M. F. (1992). Localization of growth arrest-specific genes on mouse Chromosomes 1, 7, 8, 11, 13, and 16. Mammalian Genome, 2(2), 130-134. https://doi.org/10.1007/BF00353861