Localization of foot-and-mouth disease viral antigens in mammary gland of infected cows.

J. H. Blackwell, Tilahun Yilma

Research output: Contribution to journalArticle

10 Scopus citations


Virolactias as a result of foot-and-mouth disease infection in dairy cattle would indicate active virus replication in the bovine mammary gland. In the present study, virus was readily detected throughout the mammary gland by infectivity assay after cows were exposed to the virus either by aerosol or by a combination of intramammary-IV inoculation. Furthermore, immunofluorescent and hematoxylin and eosin staining of alternate frozen sections showed viral antigens in rounded alveolar cells with pyknotic nuclei.

Original languageEnglish (US)
Pages (from-to)770-773
Number of pages4
JournalAmerican Journal of Veterinary Research
Issue number5
StatePublished - May 1981
Externally publishedYes


ASJC Scopus subject areas

  • veterinary(all)

Cite this