LipidBlast in silico tandem mass spectrometry database for lipid identification

Tobias Kind, Kwang Hyeon Liu, Do Yup Lee, Brian Defelice, John K. Meissen, Oliver Fiehn

Research output: Contribution to journalArticle

387 Scopus citations

Abstract

Current tandem mass spectral libraries for lipid annotations in metabolomics are limited in size and diversity. We provide a freely available computer-generated tandem mass spectral library of 212,516 spectra covering 119,200 compounds from 26 lipid compound classes, including phospholipids, glycerolipids, bacterial lipoglycans and plant glycolipids. We show platform independence by using tandem mass spectra from 40 different mass spectrometer types including low-resolution and high-resolution instruments.

Original languageEnglish (US)
Pages (from-to)755-758
Number of pages4
JournalNature Methods
Volume10
Issue number8
DOIs
StatePublished - Aug 2013

ASJC Scopus subject areas

  • Biotechnology
  • Molecular Biology
  • Biochemistry
  • Cell Biology

Fingerprint Dive into the research topics of 'LipidBlast in silico tandem mass spectrometry database for lipid identification'. Together they form a unique fingerprint.

  • Cite this

    Kind, T., Liu, K. H., Lee, D. Y., Defelice, B., Meissen, J. K., & Fiehn, O. (2013). LipidBlast in silico tandem mass spectrometry database for lipid identification. Nature Methods, 10(8), 755-758. https://doi.org/10.1038/nmeth.2551