Linkage mapping detects two secondary microdeletions in cell hybrid HHW1064, used to isolate DNA probes from within 5q11.2→q13.3

L. E. Bernard; John Douglas Mcpherson; J. J. Wasmuth; C. N. Kreklywich; L. M. Brzustowicz; S. Wood

doi:10.1159/000133558

Linkage mapping detects two secondary microdeletions in cell hybrid HHW1064, used to isolate DNA probes from within 5q11.2→q13.3

L. E. Bernard, John Douglas Mcpherson, J. J. Wasmuth, C. N. Kreklywich, L. M. Brzustowicz, S. Wood

Biochemistry and Molecular Medicine

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The somatic cell hybrid HHW1064 contains a single human chromosome 5 with an interstitial deletion for 5q11.2→q13.3. Twenty human clones were isolated by Alu-PCR differential hybridization. Mapping these clones indicates that HHW1064 contains two additional secondary microdeletions.

Original language	English (US)
Pages (from-to)	46-48
Number of pages	3
Journal	Cytogenetic and Genome Research
Volume	64
Issue number	1
DOIs	https://doi.org/10.1159/000133558
State	Published - 1993

ASJC Scopus subject areas

Genetics
Molecular Biology
Genetics(clinical)
Cell Biology

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Linkage mapping detects two secondary microdeletions in cell hybrid HHW1064, used to isolate DNA probes from within 5q11.2→q13.3. / Bernard, L. E.; Mcpherson, John Douglas; Wasmuth, J. J.; Kreklywich, C. N.; Brzustowicz, L. M.; Wood, S.

In: Cytogenetic and Genome Research, Vol. 64, No. 1, 1993, p. 46-48.

Research output: Contribution to journal › Article › peer-review

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AB - The somatic cell hybrid HHW1064 contains a single human chromosome 5 with an interstitial deletion for 5q11.2→q13.3. Twenty human clones were isolated by Alu-PCR differential hybridization. Mapping these clones indicates that HHW1064 contains two additional secondary microdeletions.

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Linkage mapping detects two secondary microdeletions in cell hybrid HHW1064, used to isolate DNA probes from within 5q11.2→q13.3

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