Linkage Map

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Linkage/genetic maps provide a method for examining the relationship between traits and chromosomal location. In human genetic studies, although association tests do not require a linkage map, these maps (i.e., recombinations) are incorporated into imputation algorithms that can be a major adjunct in defining specific sequence variations associated with a trait. For other species, linkage maps can also provide a framework for positional cloning efforts and defining the position of both Mendelian and quantitative trait loci.

Original languageEnglish (US)
Title of host publicationBrenner's Encyclopedia of Genetics
Subtitle of host publicationSecond Edition
PublisherElsevier Inc.
Pages255-257
Number of pages3
ISBN (Electronic)9780080961569
ISBN (Print)9780123749840
DOIs
StatePublished - Feb 27 2013

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Keywords

  • Centimorgan
  • Chromosomal location
  • Genetic maps
  • Homology relationships
  • Imputation
  • Linkage

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Seldin, M. F. (2013). Linkage Map. In Brenner's Encyclopedia of Genetics: Second Edition (pp. 255-257). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-374984-0.00872-X