Library-based lead compound discovery: Antioxidants by an analogous synthesis\deconvolutive assay strategy

Mark J. Kurth; Lisa A. Ahlberg Randall; Chixu Chen; Christian Melander; R. Bryan Miller; Kelly McAlister; Gary Reitz; Raphael Kang; Tetsuo Nakatsu; Carter Green

Library-based lead compound discovery: Antioxidants by an analogous synthesis\deconvolutive assay strategy

Mark J. Kurth, Lisa A. Ahlberg Randall, Chixu Chen, Christian Melander, R. Bryan Miller, Kelly McAlister, Gary Reitz, Raphael Kang, Tetsuo Nakatsu, Carter Green

Chemistry

Research output: Contribution to journal › Article › peer-review

93 Scopus citations

Abstract

A two-part demonstration project is reported which utilized analogous synthesis to reliably deliver a 27-analogue library which was then evaluated for antioxidative efficiency in a resin-free (ferric thiocyanate assay) deconvolutive assay.

Original language	English (US)
Pages (from-to)	5862-5864
Number of pages	3
Journal	Journal of Organic Chemistry
Volume	59
Issue number	20
State	Published - 1994

ASJC Scopus subject areas

Organic Chemistry

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Library-based lead compound discovery : Antioxidants by an analogous synthesis\deconvolutive assay strategy. / Kurth, Mark J.; Ahlberg Randall, Lisa A.; Chen, Chixu; Melander, Christian; Bryan Miller, R.; McAlister, Kelly; Reitz, Gary; Kang, Raphael; Nakatsu, Tetsuo; Green, Carter.

In: Journal of Organic Chemistry, Vol. 59, No. 20, 1994, p. 5862-5864.

Research output: Contribution to journal › Article › peer-review

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title = "Library-based lead compound discovery: Antioxidants by an analogous synthesis\deconvolutive assay strategy",

abstract = "A two-part demonstration project is reported which utilized analogous synthesis to reliably deliver a 27-analogue library which was then evaluated for antioxidative efficiency in a resin-free (ferric thiocyanate assay) deconvolutive assay.",

author = "Kurth, {Mark J.} and {Ahlberg Randall}, {Lisa A.} and Chixu Chen and Christian Melander and {Bryan Miller}, R. and Kelly McAlister and Gary Reitz and Raphael Kang and Tetsuo Nakatsu and Carter Green",

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