Library-based lead compound discovery: Antioxidants by an analogous synthesis\deconvolutive assay strategy

Mark J. Kurth; Lisa A. Ahlberg Randall; Chixu Chen; Christian Melander; R. Bryan Miller; Kelly McAlister; Gary Reitz; Raphael Kang; Tetsuo Nakatsu; Carter Green

Library-based lead compound discovery: Antioxidants by an analogous synthesis\deconvolutive assay strategy

Mark J. Kurth, Lisa A. Ahlberg Randall, Chixu Chen, Christian Melander, R. Bryan Miller, Kelly McAlister, Gary Reitz, Raphael Kang, Tetsuo Nakatsu, Carter Green

Chemistry

Research output: Contribution to journal › Article

93 Scopus citations

Abstract

A two-part demonstration project is reported which utilized analogous synthesis to reliably deliver a 27-analogue library which was then evaluated for antioxidative efficiency in a resin-free (ferric thiocyanate assay) deconvolutive assay.

Original language	English (US)
Pages (from-to)	5862-5864
Number of pages	3
Journal	Journal of Organic Chemistry
Volume	59
Issue number	20
State	Published - 1994

ASJC Scopus subject areas

Organic Chemistry

Access to Document

Fingerprint Dive into the research topics of 'Library-based lead compound discovery: Antioxidants by an analogous synthesis\deconvolutive assay strategy'. Together they form a unique fingerprint.

Cite this

Kurth, M. J., Ahlberg Randall, L. A., Chen, C., Melander, C., Bryan Miller, R., McAlister, K., Reitz, G., Kang, R., Nakatsu, T., & Green, C. (1994). Library-based lead compound discovery: Antioxidants by an analogous synthesis\deconvolutive assay strategy. Journal of Organic Chemistry, 59(20), 5862-5864.

Library-based lead compound discovery : Antioxidants by an analogous synthesis\deconvolutive assay strategy. / Kurth, Mark J.; Ahlberg Randall, Lisa A.; Chen, Chixu; Melander, Christian; Bryan Miller, R.; McAlister, Kelly; Reitz, Gary; Kang, Raphael; Nakatsu, Tetsuo; Green, Carter.

In: Journal of Organic Chemistry, Vol. 59, No. 20, 1994, p. 5862-5864.

Research output: Contribution to journal › Article

@article{9a7cabdbca7644deb48dbcc614106ff0,

title = "Library-based lead compound discovery: Antioxidants by an analogous synthesis\deconvolutive assay strategy",

abstract = "A two-part demonstration project is reported which utilized analogous synthesis to reliably deliver a 27-analogue library which was then evaluated for antioxidative efficiency in a resin-free (ferric thiocyanate assay) deconvolutive assay.",

author = "Kurth, {Mark J.} and {Ahlberg Randall}, {Lisa A.} and Chixu Chen and Christian Melander and {Bryan Miller}, R. and Kelly McAlister and Gary Reitz and Raphael Kang and Tetsuo Nakatsu and Carter Green",

year = "1994",

language = "English (US)",

volume = "59",

pages = "5862--5864",

journal = "Journal of Organic Chemistry",

issn = "0022-3263",

publisher = "American Chemical Society",

number = "20",

}

TY - JOUR

T1 - Library-based lead compound discovery

T2 - Antioxidants by an analogous synthesis\deconvolutive assay strategy

AU - Kurth, Mark J.

AU - Ahlberg Randall, Lisa A.

AU - Chen, Chixu

AU - Melander, Christian

AU - Bryan Miller, R.

AU - McAlister, Kelly

AU - Reitz, Gary

AU - Kang, Raphael

AU - Nakatsu, Tetsuo

AU - Green, Carter

PY - 1994

Y1 - 1994

N2 - A two-part demonstration project is reported which utilized analogous synthesis to reliably deliver a 27-analogue library which was then evaluated for antioxidative efficiency in a resin-free (ferric thiocyanate assay) deconvolutive assay.

AB - A two-part demonstration project is reported which utilized analogous synthesis to reliably deliver a 27-analogue library which was then evaluated for antioxidative efficiency in a resin-free (ferric thiocyanate assay) deconvolutive assay.

UR - http://www.scopus.com/inward/record.url?scp=0028151071&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028151071&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0028151071

VL - 59

SP - 5862

EP - 5864

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

SN - 0022-3263

IS - 20

ER -