Levels-of-processing effect on internal source monitoring in schizophrenia

John D Ragland, Erin McCarthy, Warren B. Bilker, Colleen M. Brensinger, Jeffrey Valdez, Christian Kohler, Raquel E. Gur, Ruben C. Gur

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Background. Recognition can be normalized in schizophrenia by providing patients with semantic organizational strategies through a levels-of-processing (LOP) framework. However, patients may rely primarily on familiarity effects, making recognition less sensitive than source monitoring to the strength of the episodic memory trace. The current study investigates whether providing semantic organizational strategies can also normalize patients' internal source-monitoring performance. Method. Sixteen clinically stable medicated patients with schizophrenia and 15 demographically matched healthy controls were asked to identify the source of remembered words following an LOP-encoding paradigm in which they alternated between processing words on a 'shallow' perceptual versus a 'deep' semantic level. A multinomial analysis provided orthogonal measures of item recognition and source discrimination, and bootstrapping generated variance to allow for parametric analyses. LOP and group effects were tested by contrasting recognition and source-monitoring parameters for words that had been encoded during deep versus shallow processing conditions. Results. As in a previous study there were no group differences in LOP effects on recognition performance, with patients and controls benefiting equally from deep versus shallow processing. Although there were no group differences in internal source monitoring, only controls had significantly better performance for words processed during the deep encoding condition. Patient performance did not correlate with clinical symptoms or medication dose. Conclusions. Providing a deep processing semantic encoding strategy significantly improved patients' recognition performance only. The lack of a significant LOP effect on internal source monitoring in patients may reflect subtle problems in the relational binding of semantic information that are independent of strategic memory processes.

Original languageEnglish (US)
Pages (from-to)641-648
Number of pages8
JournalPsychological Medicine
Volume36
Issue number5
DOIs
StatePublished - May 2006
Externally publishedYes

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Schizophrenia
Semantics
Word Processing
Episodic Memory
Physiologic Monitoring
Recognition (Psychology)

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Psychology(all)
  • Clinical Psychology

Cite this

Ragland, J. D., McCarthy, E., Bilker, W. B., Brensinger, C. M., Valdez, J., Kohler, C., ... Gur, R. C. (2006). Levels-of-processing effect on internal source monitoring in schizophrenia. Psychological Medicine, 36(5), 641-648. https://doi.org/10.1017/S0033291706007094

Levels-of-processing effect on internal source monitoring in schizophrenia. / Ragland, John D; McCarthy, Erin; Bilker, Warren B.; Brensinger, Colleen M.; Valdez, Jeffrey; Kohler, Christian; Gur, Raquel E.; Gur, Ruben C.

In: Psychological Medicine, Vol. 36, No. 5, 05.2006, p. 641-648.

Research output: Contribution to journalArticle

Ragland, JD, McCarthy, E, Bilker, WB, Brensinger, CM, Valdez, J, Kohler, C, Gur, RE & Gur, RC 2006, 'Levels-of-processing effect on internal source monitoring in schizophrenia', Psychological Medicine, vol. 36, no. 5, pp. 641-648. https://doi.org/10.1017/S0033291706007094
Ragland, John D ; McCarthy, Erin ; Bilker, Warren B. ; Brensinger, Colleen M. ; Valdez, Jeffrey ; Kohler, Christian ; Gur, Raquel E. ; Gur, Ruben C. / Levels-of-processing effect on internal source monitoring in schizophrenia. In: Psychological Medicine. 2006 ; Vol. 36, No. 5. pp. 641-648.
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