Lesion detection and quantitation of positron emission mammography

Jinyi Qi, Ronald H. Huesman

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations


A Positron Emission Mammography (PEM) scanner dedicated to breast imaging is being developed at our laboratory. We have developed a list mode likelihood reconstruction algorithm for this scanner. Here we theoretically study the lesion detection and quantitation. The lesion detectability is studied theoretically using computer observers. We found that for the zero-order quadratic prior, the region of interest observer can achieve the performance of the prewhitening observer with a properly selected smoothing parameter. We also study the lesion quantitation using the test statistic of the region of interest observer. The theoretical expressions for the bias, variance, and ensemble mean squared error of the quantitation are derived. Computer simulations show that the theoretical predictions are in good agreement with the Monte Carlo results for both lesion detection and quantitation.

Original languageEnglish (US)
Title of host publicationIEEE Nuclear Science Symposium and Medical Imaging Conference
Number of pages5
StatePublished - 2002
Externally publishedYes
Event2001 IEEE Nuclear Science Symposium Conference Record - San Diego, CA, United States
Duration: Nov 4 2001Nov 10 2001


Other2001 IEEE Nuclear Science Symposium Conference Record
Country/TerritoryUnited States
CitySan Diego, CA

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Industrial and Manufacturing Engineering


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