Lens intermediate filaments

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


The ocular lens assembles two separate intermediate filament systems sequentially with differentiation. Canonical 8-11 nm IFs composed of Vimentin are assembled in lens epithelial cells and younger fiber cells, while the fiber cell-specific beaded filaments are switched on as fiber cell elongation initiates. Some of the key features of both filament systems are reviewed.

Original languageEnglish (US)
Pages (from-to)165-172
Number of pages8
JournalExperimental Eye Research
Issue number2
StatePublished - Feb 2 2009


  • beaded filaments
  • CP49
  • filensin
  • Intermediate filaments
  • lens
  • Phakinin
  • Phakosin
  • vimentin

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience


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