The ocular lens assembles two separate intermediate filament systems sequentially with differentiation. Canonical 8-11 nm IFs composed of Vimentin are assembled in lens epithelial cells and younger fiber cells, while the fiber cell-specific beaded filaments are switched on as fiber cell elongation initiates. Some of the key features of both filament systems are reviewed.
- beaded filaments
- Intermediate filaments
ASJC Scopus subject areas
- Sensory Systems
- Cellular and Molecular Neuroscience