Lens intermediate filaments

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The ocular lens assembles two separate intermediate filament systems sequentially with differentiation. Canonical 8-11 nm IFs composed of Vimentin are assembled in lens epithelial cells and younger fiber cells, while the fiber cell-specific beaded filaments are switched on as fiber cell elongation initiates. Some of the key features of both filament systems are reviewed.

Original languageEnglish (US)
Pages (from-to)165-172
Number of pages8
JournalExperimental Eye Research
Volume88
Issue number2
DOIs
StatePublished - Feb 2 2009

Fingerprint

Intermediate Filaments
Lenses
Crystalline Lens
Vimentin
Epithelial Cells

Keywords

  • beaded filaments
  • CP49
  • filensin
  • Intermediate filaments
  • lens
  • Phakinin
  • Phakosin
  • vimentin

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this

Lens intermediate filaments. / FitzGerald, Paul G.

In: Experimental Eye Research, Vol. 88, No. 2, 02.02.2009, p. 165-172.

Research output: Contribution to journalArticle

FitzGerald, Paul G. / Lens intermediate filaments. In: Experimental Eye Research. 2009 ; Vol. 88, No. 2. pp. 165-172.
@article{290f218712704304938468179ac04e1a,
title = "Lens intermediate filaments",
abstract = "The ocular lens assembles two separate intermediate filament systems sequentially with differentiation. Canonical 8-11 nm IFs composed of Vimentin are assembled in lens epithelial cells and younger fiber cells, while the fiber cell-specific beaded filaments are switched on as fiber cell elongation initiates. Some of the key features of both filament systems are reviewed.",
keywords = "beaded filaments, CP49, filensin, Intermediate filaments, lens, Phakinin, Phakosin, vimentin",
author = "FitzGerald, {Paul G}",
year = "2009",
month = "2",
day = "2",
doi = "10.1016/j.exer.2008.11.007",
language = "English (US)",
volume = "88",
pages = "165--172",
journal = "Experimental Eye Research",
issn = "0014-4835",
publisher = "Academic Press Inc.",
number = "2",

}

TY - JOUR

T1 - Lens intermediate filaments

AU - FitzGerald, Paul G

PY - 2009/2/2

Y1 - 2009/2/2

N2 - The ocular lens assembles two separate intermediate filament systems sequentially with differentiation. Canonical 8-11 nm IFs composed of Vimentin are assembled in lens epithelial cells and younger fiber cells, while the fiber cell-specific beaded filaments are switched on as fiber cell elongation initiates. Some of the key features of both filament systems are reviewed.

AB - The ocular lens assembles two separate intermediate filament systems sequentially with differentiation. Canonical 8-11 nm IFs composed of Vimentin are assembled in lens epithelial cells and younger fiber cells, while the fiber cell-specific beaded filaments are switched on as fiber cell elongation initiates. Some of the key features of both filament systems are reviewed.

KW - beaded filaments

KW - CP49

KW - filensin

KW - Intermediate filaments

KW - lens

KW - Phakinin

KW - Phakosin

KW - vimentin

UR - http://www.scopus.com/inward/record.url?scp=61849139080&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=61849139080&partnerID=8YFLogxK

U2 - 10.1016/j.exer.2008.11.007

DO - 10.1016/j.exer.2008.11.007

M3 - Article

VL - 88

SP - 165

EP - 172

JO - Experimental Eye Research

JF - Experimental Eye Research

SN - 0014-4835

IS - 2

ER -