Lathyrogen‐induced malformations in baboons: A preliminary report

A. J. Steffek; Andrew G Hendrickx

doi:10.1002/tera.1420050207

Lathyrogen‐induced malformations in baboons: A preliminary report

A. J. Steffek, Andrew G Hendrickx

Cell Biology and Human Anatomy, and General

Research output: Contribution to journal › Article

6 Scopus citations

Abstract

Female baboons maintained on a timed pregnancy program were administered intramuscular, Intravenous, and oral doses of β‐aminopropionitrile (BAPN) and aminoacetonitrile (AAN) during the time of palatogenesis in this species. Resorptions, abortions, and fetuses with skeletal defects resulted. Cleft palate occurred in one set of twins following oral doses of 75 mg/kg/day AAN on days 43‐48 of pregnancy.

Original language	English (US)
Pages (from-to)	171-179
Number of pages	9
Journal	Teratology
Volume	5
Issue number	2
DOIs	https://doi.org/10.1002/tera.1420050207
State	Published - 1972

Fingerprint

ASJC Scopus subject areas

Embryology
Toxicology
Developmental Biology
Health, Toxicology and Mutagenesis

Cite this

Steffek, A. J., & Hendrickx, A. G. (1972). Lathyrogen‐induced malformations in baboons: A preliminary report. Teratology, 5(2), 171-179. https://doi.org/10.1002/tera.1420050207

@article{59560814b1bf40daa1dca32132b81510,

title = "Lathyrogen‐induced malformations in baboons: A preliminary report",

abstract = "Female baboons maintained on a timed pregnancy program were administered intramuscular, Intravenous, and oral doses of β‐aminopropionitrile (BAPN) and aminoacetonitrile (AAN) during the time of palatogenesis in this species. Resorptions, abortions, and fetuses with skeletal defects resulted. Cleft palate occurred in one set of twins following oral doses of 75 mg/kg/day AAN on days 43‐48 of pregnancy.",

author = "Steffek, {A. J.} and Hendrickx, {Andrew G}",

year = "1972",

doi = "10.1002/tera.1420050207",

language = "English (US)",

volume = "5",

pages = "171--179",

journal = "Teratology",

issn = "1542-0752",

publisher = "Wiley-Liss Inc.",

number = "2",

}

TY - JOUR

T1 - Lathyrogen‐induced malformations in baboons

T2 - A preliminary report

AU - Steffek, A. J.

AU - Hendrickx, Andrew G

PY - 1972

Y1 - 1972

N2 - Female baboons maintained on a timed pregnancy program were administered intramuscular, Intravenous, and oral doses of β‐aminopropionitrile (BAPN) and aminoacetonitrile (AAN) during the time of palatogenesis in this species. Resorptions, abortions, and fetuses with skeletal defects resulted. Cleft palate occurred in one set of twins following oral doses of 75 mg/kg/day AAN on days 43‐48 of pregnancy.

AB - Female baboons maintained on a timed pregnancy program were administered intramuscular, Intravenous, and oral doses of β‐aminopropionitrile (BAPN) and aminoacetonitrile (AAN) during the time of palatogenesis in this species. Resorptions, abortions, and fetuses with skeletal defects resulted. Cleft palate occurred in one set of twins following oral doses of 75 mg/kg/day AAN on days 43‐48 of pregnancy.

UR - http://www.scopus.com/inward/record.url?scp=0015321710&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0015321710&partnerID=8YFLogxK

U2 - 10.1002/tera.1420050207

DO - 10.1002/tera.1420050207

M3 - Article

C2 - 4554142

AN - SCOPUS:0015321710

VL - 5

SP - 171

EP - 179

JO - Teratology

JF - Teratology

SN - 1542-0752

IS - 2

ER -

Access to Document

10.1002/tera.1420050207