Latent intracellular Epstein-Barr virus DNA demonstrated in ocular posttransplant lymphoproliferative disorder mimicking granulomatous uveitis with iris nodules in a child

Mary A O'Hara, William C. Lloyd, Frank W. Scribbick, Margaret L. Gulley

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A case of intraocular posttransplant lymphoproliferative disorder (PTLD) is described in a 9-year-old female who underwent orthotopic liver transplantation at the age of 18 months. The prevalence of ophthalmic involvement in PTLD can be expected to rise with the increasing number of major organ transplantations, as well as improved survivorship. Children are particularly at risk for this posttransplant complication because they are usually seronegative for the Epstein-Barr virus (EBV) prior to transplant. Accurate diagnostic classification of PTLD to include confirmation of EBV infection carries significant therapeutic and prognostic implications.

Original languageEnglish (US)
Pages (from-to)62-63
Number of pages2
JournalJournal of AAPOS
Volume5
Issue number1
DOIs
StatePublished - Feb 2001
Externally publishedYes

Fingerprint

Lymphoproliferative Disorders
Uveitis
Iris
Human Herpesvirus 4
DNA
Epstein-Barr Virus Infections
Organ Transplantation
Liver Transplantation
Survival Rate
Transplants
Therapeutics

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Latent intracellular Epstein-Barr virus DNA demonstrated in ocular posttransplant lymphoproliferative disorder mimicking granulomatous uveitis with iris nodules in a child. / O'Hara, Mary A; Lloyd, William C.; Scribbick, Frank W.; Gulley, Margaret L.

In: Journal of AAPOS, Vol. 5, No. 1, 02.2001, p. 62-63.

Research output: Contribution to journalArticle

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