TY - JOUR
T1 - Laser irradiation of congenital heart disease
T2 - Potential for palliation and correction of intracardiac and intravascular defects
AU - Riemenschneider, Thomas A.
AU - Lee, Garrett
AU - Ikeda, Richard M.
AU - Bommer, William J
AU - Stobbe, Daniel
AU - Ogata, Claire
AU - Rebeck, Kevin
AU - Reis, Robert L.
AU - Mason, Dean T.
PY - 1983
Y1 - 1983
N2 - We examined the potential for laser irradiation of congenital heart defects, with the use of postmortem hearts and an argon ion laser with a flexible quartz fiber. Atrial septectomy was performed in five newborn hearts. Obstructive lesions were relieved by laser irradiation in valvular pulmonic and aortic stenosis, dysplastic pulmonary valve, pulmonary atresia, and coarctation of the aorta. To demonstrate the efficacy of in vivo cardiac laser surgery, atrial septectomy was also performed in an anesthetized dog model, under echocardiographic visualization, without change in heart rate or blood pressure. Our results demonstrate the feasibility of intracardiac and intravascular laser irradiation for palliation and repair of selected congenital heart diseases.
AB - We examined the potential for laser irradiation of congenital heart defects, with the use of postmortem hearts and an argon ion laser with a flexible quartz fiber. Atrial septectomy was performed in five newborn hearts. Obstructive lesions were relieved by laser irradiation in valvular pulmonic and aortic stenosis, dysplastic pulmonary valve, pulmonary atresia, and coarctation of the aorta. To demonstrate the efficacy of in vivo cardiac laser surgery, atrial septectomy was also performed in an anesthetized dog model, under echocardiographic visualization, without change in heart rate or blood pressure. Our results demonstrate the feasibility of intracardiac and intravascular laser irradiation for palliation and repair of selected congenital heart diseases.
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U2 - 10.1016/0002-8703(83)90050-9
DO - 10.1016/0002-8703(83)90050-9
M3 - Article
C2 - 6650361
AN - SCOPUS:0021088004
VL - 106
SP - 1389
EP - 1393
JO - American Heart Journal
JF - American Heart Journal
SN - 0002-8703
IS - 6
ER -