Laser irradiation of congenital heart disease: Potential for palliation and correction of intracardiac and intravascular defects

Thomas A. Riemenschneider, Garrett Lee, Richard M. Ikeda, William J Bommer, Daniel Stobbe, Claire Ogata, Kevin Rebeck, Robert L. Reis, Dean T. Mason

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

We examined the potential for laser irradiation of congenital heart defects, with the use of postmortem hearts and an argon ion laser with a flexible quartz fiber. Atrial septectomy was performed in five newborn hearts. Obstructive lesions were relieved by laser irradiation in valvular pulmonic and aortic stenosis, dysplastic pulmonary valve, pulmonary atresia, and coarctation of the aorta. To demonstrate the efficacy of in vivo cardiac laser surgery, atrial septectomy was also performed in an anesthetized dog model, under echocardiographic visualization, without change in heart rate or blood pressure. Our results demonstrate the feasibility of intracardiac and intravascular laser irradiation for palliation and repair of selected congenital heart diseases.

Original languageEnglish (US)
Pages (from-to)1389-1393
Number of pages5
JournalAmerican Heart Journal
Volume106
Issue number6
DOIs
StatePublished - 1983
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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    Riemenschneider, T. A., Lee, G., Ikeda, R. M., Bommer, W. J., Stobbe, D., Ogata, C., Rebeck, K., Reis, R. L., & Mason, D. T. (1983). Laser irradiation of congenital heart disease: Potential for palliation and correction of intracardiac and intravascular defects. American Heart Journal, 106(6), 1389-1393. https://doi.org/10.1016/0002-8703(83)90050-9