Abstract
Invasive cutaneous melanoma is a growing health concern. Although surgical excision can effectively treat in situ tumors, use for metastatic melanoma is limited. Laser and light-based therapies may be a valuable palliative treatment option for patients with stage III and stage IV cutaneous metastatic melanoma. Our goal is to review the published literature and provide evidence-based recommendations on laser and light-based palliative therapies for metastatic melanoma. A search of the databases Pubmed, EMBASE, Web of Science, and CINAHL was performed on March 10, 2016. Key search terms were related to melanoma, laser, and light-based modalities. Our search initially identified 13,923 articles and 27 original articles met inclusion criteria for our review. Grade of recommendation: C for non-fractionated carbon dioxide laser, Grade of recommendation: D for fractionated carbon dioxide laser, ruby laser, neodymium laser, near-infrared diode laser, and photodynamic therapy. Non-fractionated carbon dioxide laser had the best palliative efficacy of the reviewed laser and light-based therapies, while other treatment modalities may have potential as adjunctive therapy to standard of care.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 229-242 |
| Number of pages | 14 |
| Journal | Archives of Dermatological Research |
| Volume | 309 |
| Issue number | 4 |
| DOIs | |
| State | Published - May 1 2017 |
Fingerprint
Keywords
- Laser
- Melanoma
- Palliative care
- Photodynamic therapy
- Phototherapy
- Quality-of-life
ASJC Scopus subject areas
- Dermatology
Cite this
Laser and light-based therapy for cutaneous and soft-tissue metastases of malignant melanoma : a systematic review. / Austin, Evan; Mamalis, Andrew; Ho, Derek; Jagdeo, Jared.
In: Archives of Dermatological Research, Vol. 309, No. 4, 01.05.2017, p. 229-242.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Laser and light-based therapy for cutaneous and soft-tissue metastases of malignant melanoma
T2 - a systematic review
AU - Austin, Evan
AU - Mamalis, Andrew
AU - Ho, Derek
AU - Jagdeo, Jared
PY - 2017/5/1
Y1 - 2017/5/1
N2 - Invasive cutaneous melanoma is a growing health concern. Although surgical excision can effectively treat in situ tumors, use for metastatic melanoma is limited. Laser and light-based therapies may be a valuable palliative treatment option for patients with stage III and stage IV cutaneous metastatic melanoma. Our goal is to review the published literature and provide evidence-based recommendations on laser and light-based palliative therapies for metastatic melanoma. A search of the databases Pubmed, EMBASE, Web of Science, and CINAHL was performed on March 10, 2016. Key search terms were related to melanoma, laser, and light-based modalities. Our search initially identified 13,923 articles and 27 original articles met inclusion criteria for our review. Grade of recommendation: C for non-fractionated carbon dioxide laser, Grade of recommendation: D for fractionated carbon dioxide laser, ruby laser, neodymium laser, near-infrared diode laser, and photodynamic therapy. Non-fractionated carbon dioxide laser had the best palliative efficacy of the reviewed laser and light-based therapies, while other treatment modalities may have potential as adjunctive therapy to standard of care.
AB - Invasive cutaneous melanoma is a growing health concern. Although surgical excision can effectively treat in situ tumors, use for metastatic melanoma is limited. Laser and light-based therapies may be a valuable palliative treatment option for patients with stage III and stage IV cutaneous metastatic melanoma. Our goal is to review the published literature and provide evidence-based recommendations on laser and light-based palliative therapies for metastatic melanoma. A search of the databases Pubmed, EMBASE, Web of Science, and CINAHL was performed on March 10, 2016. Key search terms were related to melanoma, laser, and light-based modalities. Our search initially identified 13,923 articles and 27 original articles met inclusion criteria for our review. Grade of recommendation: C for non-fractionated carbon dioxide laser, Grade of recommendation: D for fractionated carbon dioxide laser, ruby laser, neodymium laser, near-infrared diode laser, and photodynamic therapy. Non-fractionated carbon dioxide laser had the best palliative efficacy of the reviewed laser and light-based therapies, while other treatment modalities may have potential as adjunctive therapy to standard of care.
KW - Laser
KW - Melanoma
KW - Palliative care
KW - Photodynamic therapy
KW - Phototherapy
KW - Quality-of-life
UR - http://www.scopus.com/inward/record.url?scp=85015702517&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85015702517&partnerID=8YFLogxK
U2 - 10.1007/s00403-017-1720-9
DO - 10.1007/s00403-017-1720-9
M3 - Review article
C2 - 28314913
AN - SCOPUS:85015702517
VL - 309
SP - 229
EP - 242
JO - Archives of Dermatological Research
JF - Archives of Dermatological Research
SN - 0340-3696
IS - 4
ER -