Laryngopharyngeal reflux: Current concepts in pathophysiology, diagnosis, and treatment

Catherine J. Rees, Peter C Belafsky

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


Laryngopharyngeal reflux (LPR) is the backflow of gastric contents into the pharynx and larynx. The diagnosis of LPR is primarily based on symptoms, including dysphonia, dysphagia, globus, throat-clearing, and post-nasal drip. The gold standard for diagnosis is dual-probe 24-hour pH testing with the upper probe positioned above the upper oesophageal sphincter. Treatment may require 3 months or more of twice-daily proton pump inhibitors along with lifestyle modifications. This review details the pathophysiology, symptoms, findings, treatment, and current controversies in LPR.

Original languageEnglish (US)
Pages (from-to)245-253
Number of pages9
JournalInternational Journal of Speech-Language Pathology
Issue number4
StatePublished - 2008


  • Gastroesophageal reflux
  • Laryngopharyngeal reflux
  • pH testing
  • Proton pump inhibitor

ASJC Scopus subject areas

  • Otorhinolaryngology
  • LPN and LVN
  • Speech and Hearing
  • Research and Theory


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