Laryngopharyngeal reflux: Current concepts in pathophysiology, diagnosis, and treatment

Catherine J. Rees; Peter C Belafsky

doi:10.1080/17549500701862287

Laryngopharyngeal reflux: Current concepts in pathophysiology, diagnosis, and treatment

Catherine J. Rees, Peter C Belafsky

Otolaryngology

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Laryngopharyngeal reflux (LPR) is the backflow of gastric contents into the pharynx and larynx. The diagnosis of LPR is primarily based on symptoms, including dysphonia, dysphagia, globus, throat-clearing, and post-nasal drip. The gold standard for diagnosis is dual-probe 24-hour pH testing with the upper probe positioned above the upper oesophageal sphincter. Treatment may require 3 months or more of twice-daily proton pump inhibitors along with lifestyle modifications. This review details the pathophysiology, symptoms, findings, treatment, and current controversies in LPR.

Original language	English (US)
Pages (from-to)	245-253
Number of pages	9
Journal	International Journal of Speech-Language Pathology
Volume	10
Issue number	4
DOIs	https://doi.org/10.1080/17549500701862287
State	Published - 2008

Keywords

Gastroesophageal reflux
Laryngopharyngeal reflux
pH testing
Proton pump inhibitor

ASJC Scopus subject areas

Otorhinolaryngology
LPN and LVN
Speech and Hearing
Research and Theory

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AB - Laryngopharyngeal reflux (LPR) is the backflow of gastric contents into the pharynx and larynx. The diagnosis of LPR is primarily based on symptoms, including dysphonia, dysphagia, globus, throat-clearing, and post-nasal drip. The gold standard for diagnosis is dual-probe 24-hour pH testing with the upper probe positioned above the upper oesophageal sphincter. Treatment may require 3 months or more of twice-daily proton pump inhibitors along with lifestyle modifications. This review details the pathophysiology, symptoms, findings, treatment, and current controversies in LPR.

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KW - pH testing

KW - Proton pump inhibitor

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Laryngopharyngeal reflux: Current concepts in pathophysiology, diagnosis, and treatment

Abstract

Keywords

ASJC Scopus subject areas

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