Language development and fragile X syndrome: Profiles, syndrome- specificity, and within-syndrome differences

Leonard J Abbeduto, Nancy Brady, Sara T. Kover

Research output: Contribution to journalArticle

125 Scopus citations

Abstract

Fragile X syndrome (FXS) is the leading inherited cause of mental retardation. In this article, we review what is known about the language and related problems of individuals with FXS. In doing so, we focus on the syndrome-specific features of the language phenotype and on the organismic (i.e., genetic and individual neurocognitive and behavioral) and environmental factors associated with within-syndrome variation in the phenotype. We also briefly review those aspects of the behavioral phenotype of FXS that are relevant for understanding syndrome-specific features of, and within-syndrome variability in, language. The review includes summaries of research on the prelinguistic foundations for language development and on each of the major components of language (i.e., vocabulary, morphosyntax, and pragmatics). Throughout the review, we point out implications of existing research for intervention as well as directions for future research,

Original languageEnglish (US)
Pages (from-to)36-46
Number of pages11
JournalMental Retardation and Developmental Disabilities Research Reviews
Volume13
Issue number1
DOIs
StatePublished - 2007
Externally publishedYes

Keywords

  • Autism
  • Communication
  • Fragile X syndrome
  • Language
  • Mental retardation

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neuropsychology and Physiological Psychology
  • Genetics(clinical)

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