Label-Free screening of protein binding to small molecule compound microarrays with a high-throughput optical scanning microscope

J. P. Landry, Y. Y. Fei, Y. S. Sun, J. T. Luo, Kit Lam, X. D. Zhu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Using a label-free high-throughput optical scanning microscope we detected endpoints and binding kinetics of vascular endothelial growth factor (VEGF) protein with microarrays of small molecule compounds from the NCI Developmental Therapeutics Program.

Original languageEnglish (US)
Title of host publicationOptics InfoBase Conference Papers
PublisherOptical Society of America
ISBN (Print)9781557528780
StatePublished - 2009
EventFrontiers in Optics, FiO 2009 - San Jose, CA, United States
Duration: Oct 11 2009Oct 15 2009

Other

OtherFrontiers in Optics, FiO 2009
CountryUnited States
CitySan Jose, CA
Period10/11/0910/15/09

Fingerprint

Microarrays
Labels
Screening
Microscopes
screening
microscopes
Throughput
proteins
Proteins
Scanning
Molecules
Kinetics
scanning
kinetics
molecules
Intercellular Signaling Peptides and Proteins
Protein Binding

ASJC Scopus subject areas

  • Instrumentation
  • Atomic and Molecular Physics, and Optics

Cite this

Landry, J. P., Fei, Y. Y., Sun, Y. S., Luo, J. T., Lam, K., & Zhu, X. D. (2009). Label-Free screening of protein binding to small molecule compound microarrays with a high-throughput optical scanning microscope. In Optics InfoBase Conference Papers Optical Society of America.

Label-Free screening of protein binding to small molecule compound microarrays with a high-throughput optical scanning microscope. / Landry, J. P.; Fei, Y. Y.; Sun, Y. S.; Luo, J. T.; Lam, Kit; Zhu, X. D.

Optics InfoBase Conference Papers. Optical Society of America, 2009.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Landry, JP, Fei, YY, Sun, YS, Luo, JT, Lam, K & Zhu, XD 2009, Label-Free screening of protein binding to small molecule compound microarrays with a high-throughput optical scanning microscope. in Optics InfoBase Conference Papers. Optical Society of America, Frontiers in Optics, FiO 2009, San Jose, CA, United States, 10/11/09.
Landry JP, Fei YY, Sun YS, Luo JT, Lam K, Zhu XD. Label-Free screening of protein binding to small molecule compound microarrays with a high-throughput optical scanning microscope. In Optics InfoBase Conference Papers. Optical Society of America. 2009
Landry, J. P. ; Fei, Y. Y. ; Sun, Y. S. ; Luo, J. T. ; Lam, Kit ; Zhu, X. D. / Label-Free screening of protein binding to small molecule compound microarrays with a high-throughput optical scanning microscope. Optics InfoBase Conference Papers. Optical Society of America, 2009.
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