Label-free optical detection of biomolecular reaction kinetics in microarray format for high-throughput screening applications

Y. S. Sun, J. P. Landry, Y. Y. Fei, J. T. Luo, Kit Lam, X. D. Zhu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Using a combination of an oblique-incidence reflectivity difference (OI-RD) scanning microscope and a customized 8-chamber sample cartridge, we detect 300 surface-immobilized molecular targets reacting with up to 8 different analytes simultaneously on a single slide.

Original languageEnglish (US)
Title of host publication2009 Conference on Lasers and Electro-Optics and 2009 Conference on Quantum Electronics and Laser Science Conference, CLEO/QELS 2009
StatePublished - 2009
Event2009 Conference on Lasers and Electro-Optics and 2009 Conference on Quantum Electronics and Laser Science Conference, CLEO/QELS 2009 - Baltimore, MD, United States
Duration: Jun 2 2009Jun 4 2009

Other

Other2009 Conference on Lasers and Electro-Optics and 2009 Conference on Quantum Electronics and Laser Science Conference, CLEO/QELS 2009
CountryUnited States
CityBaltimore, MD
Period6/2/096/4/09

Fingerprint

Microarrays
Reaction kinetics
Labels
Screening
Microscopes
Throughput
Scanning

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials

Cite this

Sun, Y. S., Landry, J. P., Fei, Y. Y., Luo, J. T., Lam, K., & Zhu, X. D. (2009). Label-free optical detection of biomolecular reaction kinetics in microarray format for high-throughput screening applications. In 2009 Conference on Lasers and Electro-Optics and 2009 Conference on Quantum Electronics and Laser Science Conference, CLEO/QELS 2009 [5225737]

Label-free optical detection of biomolecular reaction kinetics in microarray format for high-throughput screening applications. / Sun, Y. S.; Landry, J. P.; Fei, Y. Y.; Luo, J. T.; Lam, Kit; Zhu, X. D.

2009 Conference on Lasers and Electro-Optics and 2009 Conference on Quantum Electronics and Laser Science Conference, CLEO/QELS 2009. 2009. 5225737.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Sun, YS, Landry, JP, Fei, YY, Luo, JT, Lam, K & Zhu, XD 2009, Label-free optical detection of biomolecular reaction kinetics in microarray format for high-throughput screening applications. in 2009 Conference on Lasers and Electro-Optics and 2009 Conference on Quantum Electronics and Laser Science Conference, CLEO/QELS 2009., 5225737, 2009 Conference on Lasers and Electro-Optics and 2009 Conference on Quantum Electronics and Laser Science Conference, CLEO/QELS 2009, Baltimore, MD, United States, 6/2/09.
Sun YS, Landry JP, Fei YY, Luo JT, Lam K, Zhu XD. Label-free optical detection of biomolecular reaction kinetics in microarray format for high-throughput screening applications. In 2009 Conference on Lasers and Electro-Optics and 2009 Conference on Quantum Electronics and Laser Science Conference, CLEO/QELS 2009. 2009. 5225737
Sun, Y. S. ; Landry, J. P. ; Fei, Y. Y. ; Luo, J. T. ; Lam, Kit ; Zhu, X. D. / Label-free optical detection of biomolecular reaction kinetics in microarray format for high-throughput screening applications. 2009 Conference on Lasers and Electro-Optics and 2009 Conference on Quantum Electronics and Laser Science Conference, CLEO/QELS 2009. 2009.
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